3-对氟苯基-2-甲基-4(3h)-喹唑烷酮结构式
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常用名 | 3-对氟苯基-2-甲基-4(3h)-喹唑烷酮 | 英文名 | 3-(p-fluorophenyl)-2-methyl-4(3h)-quinazolinon |
|---|---|---|---|---|
| CAS号 | 1897-80-9 | 分子量 | 254.25900 | |
| 密度 | 1.25g/cm3 | 沸点 | 411.4ºC at 760mmHg | |
| 分子式 | C15H11FN2O | 熔点 | N/A | |
| MSDS | N/A | 闪点 | 202.6ºC |
3-对氟苯基-2-甲基-4(3h)-喹唑烷酮用途WAY-622252 是一种活性分子,可用于淀粉样蛋白疾病和突触核蛋白病的研究。 |
| 中文名 | 3-对氟苯基-2-甲基-4(3h)-喹唑烷酮 |
|---|---|
| 英文名 | 3-(4-fluorophenyl)-2-methylquinazolin-4-one |
| 英文别名 | 更多 |
| 密度 | 1.25g/cm3 |
|---|---|
| 沸点 | 411.4ºC at 760mmHg |
| 分子式 | C15H11FN2O |
| 分子量 | 254.25900 |
| 闪点 | 202.6ºC |
| 精确质量 | 254.08600 |
| PSA | 34.89000 |
| LogP | 2.83320 |
| InChIKey | RONAQXGMJDYSJD-UHFFFAOYSA-N |
| SMILES | Cc1nc2ccccc2c(=O)n1-c1ccc(F)cc1 |
| 蒸汽压 | 5.62E-07mmHg at 25°C |
| 折射率 | 1.621 |
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~36%
3-对氟苯基-2-甲基-4(3... 1897-80-9 |
| 文献:Hilmy, Khalid Mohamed Hassan; Mogensen, Joergen; Pedersen, Erik B. Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry, 1987 , vol. 41, p. 467 - 468 |
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~53%
3-对氟苯基-2-甲基-4(3... 1897-80-9 |
| 文献:Mahindroo, Neeraj; Ahmed, Zabeer; Bhagat, Asha; Bedi, Kasturi Lal; Khajuria, Ravi Kant; Kapoor, Vijay Kumar; Dhar, Kanaya Lal Medicinal Chemistry Research, 2005 , vol. 14, # 6 p. 347 - 368 |
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~%
3-对氟苯基-2-甲基-4(3... 1897-80-9 |
| 文献:Mahindroo, Neeraj; Ahmed, Zabeer; Bhagat, Asha; Bedi, Kasturi Lal; Khajuria, Ravi Kant; Kapoor, Vijay Kumar; Dhar, Kanaya Lal Medicinal Chemistry Research, 2005 , vol. 14, # 6 p. 347 - 368 |
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实验名称:Primary cell-based high-throughput screening assay for identification of compounds th...
来源:Johns Hopkins Ion Channel Center
靶标:regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id:JHICC_RGS_Act_HTS
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实验名称:Luminescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id:OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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实验名称:QFRET-based biochemical primary high throughput screening assay to identify exosite i...
来源:The Scripps Research Institute Molecular Screening Center
靶标:disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id:ADAM17_INH_QFRET_1536_1X%INH PRUN
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实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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实验名称:uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
来源:Burnham Center for Chemical Genomics
靶标:N/A
External Id:BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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实验名称:High throughput fluorescence intensity-based biochemical assay to screen for small mo...
来源:University of Pittsburgh Molecular Library Screening Center
靶标:furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id:MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
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实验名称:Bronchodilatory activity in histamine-precontracted Cavia porcellus (guinea pig) trac...
来源:ChEMBL
靶标:Tissue
External Id:CHEMBL3054146
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实验名称:Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
来源:Broad Institute
靶标:FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id:2147-01_Inhibitor_SinglePoint_HTS_Activity
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实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify pos...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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实验名称:Fluorescence polarization-based biochemical high throughput primary assay to identify...
来源:The Scripps Research Institute Molecular Screening Center
靶标:RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id:SIAE_INH_FP_1536_1X%INH PRUN
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| B 228 |
| 3-<4-Fluor-phenyl>-2-methyl-3H-chinazolin-4-on |