2-chloro-4-[4-[1-[(2R)-2-hydroxy-3-methyl-2-(trifluoromethyl)butanoyl]-4-piperidyl]-1-piperidyl]-N,N-dimethyl-benzamide

• 常用名: 2-chloro-4-[4-[1-[(2R)-2-hydroxy-3-methyl-2-(trifluoromethyl)butanoyl]-4-piperidyl]-1-piperidyl]-N,N-dimethyl-benzamide
• 英文名: 2-chloro-4-[4-[1-[(2R)-2-hydroxy-3-methyl-2-(trifluoromethyl)butanoyl]-4-piperidyl]-1-piperidyl]-N,N-dimethyl-benzamide
• CAS号: 1908434-16-1
• 分子量: 518.0
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₅H₃₅ClF₃N₃O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-chloro-4-[4-[1-[(2R)-2-hydroxy-3-methyl-2-(trifluoromethyl)butanoyl]-4-piperidyl]-1-piperidyl]-N,N-dimethyl-benzamide

物理化学性质

• 分子式: C₂₅H₃₅ClF₃N₃O₃
• 分子量: 518.0
• InChIKey: POYRTHYMXFSQBJ-XMMPIXPASA-N
• SMILES: CC(C)C(O)(C(=O)N1CCC(C2CCN(c3ccc(C(=O)N(C)C)c(Cl)c3)CC2)CC1)C(F)(F)F

靶点实验

查看更多实验

实验名称：Increase in apoE level in CSF of rhesus monkey at 10 and 20 mg/kg, po administered fo... 来源：ChEMBL 靶标：Macaca mulatta External Id：CHEMBL3811158

实验名称：Increase in LDL cholesterol level in rhesus monkey at 10 to 20 mg/kg, po qd for 2 wee... 来源：ChEMBL 靶标：Macaca mulatta External Id：CHEMBL3811040

实验名称：Reversal of hyperlocomotary behavior in Tg2576 transgenic mouse at 50 mg/kg, sc admin... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3811039

实验名称：Increase in amyloid beta40 in CSF of rhesus monkey at 20 mg/kg, po administered for 2... 来源：ChEMBL 靶标：Macaca mulatta External Id：CHEMBL3811410

实验名称：Increase in apoE level in CSF of Wistar Han rat at 100 mg/kg, sc dosed for 4 days by ... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3811026

实验名称：Oral bioavailability in rhesus monkey 来源：ChEMBL 靶标：Macaca mulatta External Id：CHEMBL3811025

实验名称：Volume of distribution at steady state in rhesus monkey 来源：ChEMBL 靶标：Macaca mulatta External Id：CHEMBL3811024

实验名称：Half life of compound in rhesus monkey 来源：ChEMBL 靶标：Macaca mulatta External Id：CHEMBL3811023

实验名称：Activation of LXR in Tg2576 transgenic mouse assessed increase in brain ABCA1 level a... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3811030

实验名称：Toxicity in Wistar Han rat assessed as change in plasma triglyceride level at 100 mg/... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3811029

共37条，当前第1页，共4页

1

2

3

4