US10214537, Example 17

• 常用名: US10214537, Example 17
• 英文名: US10214537, Example 17
• CAS号: 1911558-79-6
• 分子量: 445.6
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₅H₃₁N₇O
• 熔点: N/A
• 闪点: N/A

US10214537, Example 17名称

• 英文名: US10214537, Example 17

US10214537, Example 17物理化学性质

• 分子式: C₂₅H₃₁N₇O
• 分子量: 445.6
• InChIKey: BAELSNZYFKEGDO-UHFFFAOYSA-N
• SMILES: CN(C)C(C)(C)c1cccc(-c2cc(-c3ccnn3C3CCOCC3)c3c(N)ncnn23)c1

US10214537, Example 17靶点实验

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实验名称：Stability in human liver microsomes assessed as parent compound remaining at 0.5 uM a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4427870

实验名称：ADP-Glo Format PI3K Assay from US Patent US10214537: "Bicyclic heteroaryl amine compo... 来源：BindingDB 靶标：N/A External Id：BindingDB_2230_1

实验名称：Stability in mouse liver microsomes assessed as parent compound remaining at 0.5 uM a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4427871

实验名称：Inhibition of PI3Kdelta in BCR-stimulated human B cells assessed as suppression of CD... 来源：ChEMBL 靶标：Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform External Id：CHEMBL4427873

实验名称：Clearance in mouse 来源：ChEMBL 靶标：N/A External Id：CHEMBL4427876

实验名称：Volume of distribution in mouse 来源：ChEMBL 靶标：N/A External Id：CHEMBL4427877

实验名称：Inhibition of PI3Kdelta (unknown origin) using PIP2:PS as substrate incubated for 3 h... 来源：ChEMBL 靶标：Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform External Id：CHEMBL4427866

实验名称：Selectivity ratio of IC50 for PI3Kalpha (unknown origin) to IC50 for PI3Kdelta (unkno... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4427867

实验名称：Selectivity ratio of IC50 for PI3Kbeta (unknown origin) to IC50 for PI3Kdelta (unknow... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4427868

实验名称：Selectivity ratio of IC50 for PI3Kgamma (unknown origin) to IC50 for PI3Kdelta (unkno... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4427869

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