LYPLAL1-IN-11

• 常用名: LYPLAL1-IN-11
• 英文名: LYPLAL1-IN-11
• CAS号: 1966129-74-7
• 分子量: 539.59
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₉H₂₉N₇O₄
• 熔点: N/A
• 闪点: N/A

LYPLAL1-IN-11用途

LYPLAL1-IN-1 (Compound 11) 是溶血磷脂酶 1 (LYPLAL1) 的选择性共价小分子抑制剂,IC50 值为 0.006 μM。 LYPLAL1-IN-1 增加葡萄糖产量。

LYPLAL1-IN-11名称

• 英文名: LYPLAL1-IN-1

LYPLAL1-IN-11生物活性

• 描述: LYPLAL1-IN-1 (Compound 11) 是溶血磷脂酶 1 (LYPLAL1) 的选择性共价小分子抑制剂,IC50 值为 0.006 μM。 LYPLAL1-IN-1 增加葡萄糖产量。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 代谢疾病
• 靶点实验:

  IC50: 0.006 μM (LYPLAL1-IN-1)[1]

• 参考文献:

  [1]. Ahn K, et al. Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism. ACS Chem Biol. 2016 Sep 16;11(9):2529-40.

LYPLAL1-IN-11物理化学性质

• 分子式: C₂₉H₂₉N₇O₄
• 分子量: 539.59
• 储存条件: 2-8°C，密封，干燥

LYPLAL1-IN-11靶点实验

查看更多实验

实验名称：Fraction unbound in Wistar Han rat plasma at 2 uM incubated for 6 hrs by equilibrium ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4376708

实验名称：Fraction unbound in Wistar Han rat white adipose tissue at 2 uM incubated for 6 hrs b... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4376709

实验名称：Fraction unbound in Wistar Han rat brain at 2 uM incubated for 6 hrs by equilibrium d... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4376710

实验名称：Fraction unbound in Wistar Han rat heart at 2 uM incubated for 6 hrs by equilibrium d... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4376711

实验名称：Fraction unbound in Wistar Han rat liver at 2 uM incubated for 6 hrs by equilibrium d... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4376712

实验名称：Fraction unbound in Wistar Han rat skeletal muscle at 2 uM incubated for 6 hrs by equ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4376713

实验名称：Total plasma concentration in Wistar Han rat at 1 to 2 mg/kg, iv infused for 10 to 20... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4376714

实验名称：Drug concentration in total white adipose tissue in Wistar Han rat at 1 to 2 mg/kg, i... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4376715

实验名称：Unbound tissue partition coefficient, ratio of drug level in skeletal muscle to plasm... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4376724

实验名称：Apparent permeability of the compound across dog RRCK cells by MDCK-LE assay 来源：ChEMBL 靶标：N/A External Id：CHEMBL4376726

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