2-[(1S)-1-[(6-amino-5-cyanopyrimidin-4-yl)amino]ethyl]-5-fluoro-N-methyl-3-pyridin-2-ylquinoline-4-carboxamide

• 常用名: 2-[(1S)-1-[(6-amino-5-cyanopyrimidin-4-yl)amino]ethyl]-5-fluoro-N-methyl-3-pyridin-2-ylquinoline-4-carboxamide
• 英文名: 2-[(1S)-1-[(6-amino-5-cyanopyrimidin-4-yl)amino]ethyl]-5-fluoro-N-methyl-3-pyridin-2-ylquinoline-4-carboxamide
• CAS号: 1975263-74-1
• 分子量: 442.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₁₉FN₈O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-[(1S)-1-[(6-amino-5-cyanopyrimidin-4-yl)amino]ethyl]-5-fluoro-N-methyl-3-pyridin-2-ylquinoline-4-carboxamide

物理化学性质

• 分子式: C₂₃H₁₉FN₈O
• 分子量: 442.4
• InChIKey: CCLUQQJLBVGECO-LBPRGKRZSA-N
• SMILES: CNC(=O)c1c(-c2ccccn2)c(C(C)Nc2ncnc(N)c2C#N)nc2cccc(F)c12

靶点实验

查看更多实验

实验名称：Oral bioavailability in Sprague-Dawley rat at 2 mg/kg by by LC-MS method 来源：ChEMBL 靶标：N/A External Id：CHEMBL4428730

实验名称：Inhibition of PI3Kdelta in IgM membrane only homozygous transgenic mouse assessed as ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4428731

实验名称：Inhibition of PI3Kdelta in IgM membrane only homozygous transgenic mouse assessed as ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4428732

实验名称：Toxicity in Sprague-Dawley rat assessed as drug tolerability at 0.001 to 0.1 mg/kg me... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4428737

实验名称：Selectivity index, ratio of IC50 for inhibition of polyHis tagged full length recombi... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4428722

实验名称：Selectivity index, ratio of IC50 for inhibition of polyHis tagged full length recombi... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4428723

实验名称：Selectivity index, ratio of IC50 for inhibition of N-terminal polyHis tagged full len... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4428724

实验名称：Inhibition of PI3Kdelta in human whole blood assessed as inhibition of Anti-IgD antib... 来源：ChEMBL 靶标：Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform External Id：CHEMBL4428725

实验名称：Aqueous equilibrium solubility at room temperature after 72 hrs at pH 7.4 by HPLC 来源：ChEMBL 靶标：N/A External Id：CHEMBL4428726

实验名称：Apparent permeability in LLC-PK1 cells by LC-MS method 来源：ChEMBL 靶标：N/A External Id：CHEMBL4428727

共26条，当前第1页，共3页

1

2

3