CRT0273750

• 常用名: CRT0273750
• 英文名: CRT0273750
• CAS号: 1979939-16-6
• 分子量: 502.92
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₅H₂₂ClF₃N₄O₂
• 熔点: N/A
• 闪点: N/A

CRT0273750用途

新型有效的溶血磷脂酶自毒素抑制剂

CRT0273750名称

• 英文名: CRT0273750

CRT0273750生物活性

• 描述: 新型有效的溶血磷脂酶自毒素抑制剂

CRT0273750物理化学性质

• 分子式: C₂₅H₂₂ClF₃N₄O₂
• 分子量: 502.92
• InChIKey: HXYXHSDYBDFOFO-INIZCTEOSA-N
• SMILES: CC(NC(=O)CCc1nc2cccnc2n1Cc1ccc(OC(F)(F)F)cc1)c1ccc(Cl)cc1

CRT0273750靶点实验

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实验名称：Inhibition of ATX in human plasma assessed as decrease in hydrolysis of lysophosphati... 来源：ChEMBL 靶标：Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 External Id：CHEMBL3865063

实验名称：Intrinsic clearance in CD1 mouse liver microsomes assessed per gram of liver at 1 uM ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3865064

实验名称：Intrinsic clearance in human liver microsomes assessed per gram of liver at 1 uM in p... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3865066

实验名称：Inhibition of human recombinant ATX using Rac-1-Palmitoyl-glycero-3-phosphocholine as... 来源：ChEMBL 靶标：Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 External Id：CHEMBL3865062

实验名称：Volume of distribution at steady state in CD1 mouse at 1 mg/kg, iv administered as bo... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3865071

实验名称：Intrinsic clearance in rat liver microsomes assessed per gram of liver 来源：ChEMBL 靶标：N/A External Id：CHEMBL3865072

实验名称：Fraction unbound in mouse plasma 来源：ChEMBL 靶标：N/A External Id：CHEMBL3865073

实验名称：Fraction unbound in rat plasma 来源：ChEMBL 靶标：N/A External Id：CHEMBL3865074

实验名称：Half life in CD1 mouse blood at 1 mg/kg, iv administered as bolus dose measured up to... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3865067

实验名称：Blood clearance in CD1 mouse at 1 mg/kg, iv administered as bolus dose measured up to... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3865069

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