(2,6-二氯苯磺酰基氨基)-乙酸

• 常用名: (2,6-二氯苯磺酰基氨基)-乙酸
• 英文名: (2,5-DIMETHYL-PHENYL)-THIOUREA
• CAS号: 19818-06-5
• 分子量: 284.11600
• 密度: 1.622g/cm3
• 沸点: 486.9ºC at 760mmHg
• 分子式: C₈H₇Cl₂NO₄S
• 熔点: N/A
• 闪点: 248.3ºC

(2,6-二氯苯磺酰基氨基)-乙酸用途

(2,6-二氯苯基)磺酰基)甘氨酸是甘氨酸(HY-Y0966)衍生物[1]。

(2,6-二氯苯磺酰基氨基)-乙酸名称

• 中文名: (2,6-二氯苯磺酰基氨基)-乙酸
• 英文名: 2-[(2,6-dichlorophenyl)sulfonylamino]acetic acid

(2,6-二氯苯磺酰基氨基)-乙酸生物活性

• 描述: (2,6-二氯苯基)磺酰基)甘氨酸是甘氨酸(HY-Y0966)衍生物[1]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 体外研究: 氨基酸和氨基酸衍生物已被商业化用作能量补充剂。它们影响合成代谢激素的分泌、运动期间的燃料供应、压力相关任务期间的精神表现,并防止运动引起的肌肉损伤。它们被认为是有益的能生膳食物质[1]。
• 参考文献:

  [1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

(2,6-二氯苯磺酰基氨基)-乙酸物理化学性质

• 密度: 1.622g/cm3
• 沸点: 486.9ºC at 760mmHg
• 分子式: C₈H₇Cl₂NO₄S
• 分子量: 284.11600
• 闪点: 248.3ºC
• 精确质量: 282.94700
• PSA: 91.85000
• LogP: 2.82800
• InChIKey: QRVMUGYJNLHEJY-UHFFFAOYSA-N
• SMILES: O=C(O)CNS(=O)(=O)c1c(Cl)cccc1Cl
• 蒸汽压: 2.7E-10mmHg at 25°C

(2,6-二氯苯磺酰基氨基)-乙酸靶点实验

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实验名称：Primary cell-based high-throughput screening assay for identification of compounds th... 来源：Johns Hopkins Ion Channel Center 靶标：regulator of G-protein signaling 4 isoform 2 [Homo sapiens] External Id：JHICC_RGS_Act_HTS

实验名称：Luminescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：mu-type opioid receptor isoform MOR-1 [Homo sapiens] External Id：OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN

实验名称：QFRET-based biochemical primary high throughput screening assay to identify exosite i... 来源：The Scripps Research Institute Molecular Screening Center 靶标：disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens] External Id：ADAM17_INH_QFRET_1536_1X%INH PRUN

实验名称：Fluorescence-based cell-based primary high throughput screening assay to identify ago... 来源：The Scripps Research Institute Molecular Screening Center 靶标：muscarinic acetylcholine receptor M1 [Homo sapiens] External Id：CHRM1_AG_FLUO8_1536_1X%ACT PRUN

实验名称：uHTS identification of small molecule activators of the adaptive arm of the Unfolded ... 来源：Burnham Center for Chemical Genomics 靶标：N/A External Id：BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay

实验名称：High throughput fluorescence intensity-based biochemical assay to screen for small mo... 来源：University of Pittsburgh Molecular Library Screening Center 靶标：furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens] External Id：MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.

实验名称：Fluorescence polarization to screen for inhibitor that competite the binding of FadD2... 来源：Broad Institute 靶标：FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE) External Id：2147-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect... 来源：Broad Institute 靶标：N/A External Id：Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity

实验名称：Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste... 来源：Broad Institute 靶标：N/A External Id：7124-01_Inhibitor_SinglePoint_HTS_Activity

实验名称：qHTS of TDP-43 Inhibitors: NCGC Sytravon Library Screen 来源：NCGC External Id：tdp43-p2-repeat

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(2,6-二氯苯磺酰基氨基)-乙酸英文别名

• N-Carboxymethyl-2.6-dichlor-benzolsulfonsaeure-amid