N-[4-[(3-chloro-4-fluorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl]-5-(4-methyl-1-piperazinyl)-2-pentynamide

• 常用名: N-[4-[(3-chloro-4-fluorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl]-5-(4-methyl-1-piperazinyl)-2-pentynamide
• 英文名: N-[4-[(3-chloro-4-fluorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl]-5-(4-methyl-1-piperazinyl)-2-pentynamide
• CAS号: 198960-77-9
• 分子量: 467.9
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₂₃ClFN₇O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-[4-[(3-chloro-4-fluorophenyl)amino]pyrido[3,4-d]pyrimidin-6-yl]-5-(4-methyl-1-piperazinyl)-2-pentynamide

物理化学性质

• 分子式: C₂₃H₂₃ClFN₇O
• 分子量: 467.9
• InChIKey: VIANWBJPMVJZPN-UHFFFAOYSA-N
• SMILES: CN1CCN(CCC#CC(=O)Nc2cc3c(Nc4ccc(F)c(Cl)c4)ncnc3cn2)CC1

靶点实验

查看更多实验

实验名称：Oral bioavailability in dog at 15 mg/kg 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL853632

实验名称：Oral bioavailability in rat at 15 mg/kg 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL853631

实验名称：AUC(0-tz) in monkey at 30 mg/kg, po 来源：ChEMBL 靶标：Macaca mulatta External Id：CHEMBL853630

实验名称：AUC(0-tz) in dog at 15 mg/kg, po 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL853629

实验名称：Oral bioavailability in monkey at 30 mg/kg 来源：ChEMBL 靶标：Macaca mulatta External Id：CHEMBL853633

实验名称：Antitumor activity in SCID mice implanted with SF 767 xenografts at 40 mg/kg, po 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL853621

实验名称：Antitumor activity in NCr nu/nu mice implanted with SKOV3 xenografts at 40 mg/kg, po 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL853620

实验名称：Antitumor activity in NCr nu/nu mice implanted with H125 NSC xenografts at 40 mg/kg, ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL862535

实验名称：Antitumor activity in NCr nu/nu mice implanted with A431 xenografts at 10 mg/kg, po 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL862534

实验名称：Antitumor activity in SCID mice implanted with BXPC3 xenografts at 40 mg/kg, po 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL853622

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