9-[(1R,6R,8R,9R,10R,15R,17R,18R)-17-(6-aminopurin-9-yl)-9,18-difluoro-3-hydroxy-12-oxo-12-sulfanyl-3-sulfanylidene-2,4,7,11,13,16-hexaoxa-3lambda5,12lambda5-diphosphatricyclo[13.3.0.06,10]octadecan-8-yl]purin-6-amine

• 常用名: 9-[(1R,6R,8R,9R,10R,15R,17R,18R)-17-(6-aminopurin-9-yl)-9,18-difluoro-3-hydroxy-12-oxo-12-sulfanyl-3-sulfanylidene-2,4,7,11,13,16-hexaoxa-3lambda5,12lambda5-diphosphatricyclo[13.3.0.06,10]octadecan-8-yl]purin-6-amine
• 英文名: 9-[(1R,6R,8R,9R,10R,15R,17R,18R)-17-(6-aminopurin-9-yl)-9,18-difluoro-3-hydroxy-12-oxo-12-sulfanyl-3-sulfanylidene-2,4,7,11,13,16-hexaoxa-3lambda5,12lambda5-diphosphatricyclo[13.3.0.06,10]octadecan-8-yl]purin-6-amine
• CAS号: 2005448-86-0
• 分子量: 694.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₂₂F₂N₁₀O₈P₂S₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 9-[(1R,6R,8R,9R,10R,15R,17R,18R)-17-(6-aminopurin-9-yl)-9,18-difluoro-3-hydroxy-12-oxo-12-sulfanyl-3-sulfanylidene-2,4,7,11,13,16-hexaoxa-3lambda5,12lambda5-diphosphatricyclo[13.3.0.06,10]octadecan-8-yl]purin-6-amine

物理化学性质

• 分子式: C₂₀H₂₂F₂N₁₀O₈P₂S₂
• 分子量: 694.5
• InChIKey: IAOSONHXVQMOMS-IRYAPSAPSA-N
• SMILES: C1[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C(N=CN=C43)N)F)OP(=O)(OC[C@@H]5[C@H]([C@H]([C@@H](O5)N6C=NC7=C(N=CN=C76)N)F)OP(=S)(O1)O)S

靶点实验

查看更多实验

实验名称：Binding affinity to human STING expressed in HRK293T cells assessed as change in melt... 来源：ChEMBL 靶标：Stimulator of interferon genes protein External Id：CHEMBL5036863

实验名称：Binding affinity to wild type STING (unknown origin) assessed as change in melting te... 来源：ChEMBL 靶标：Stimulator of interferon genes protein External Id：CHEMBL5036862

实验名称：Induction of TNF-alpha production in healthy human PBMC incubated for 16 hrs 来源：ChEMBL 靶标：N/A External Id：CHEMBL5036853

实验名称：Activation of wild-type human STING expressed in human THP1-Dual cells co-expressing ... 来源：ChEMBL 靶标：Stimulator of interferon genes protein External Id：CHEMBL5036847

实验名称：Activation of wild-type human STING expressed in digitonin treated human THP1-Dual ce... 来源：ChEMBL 靶标：Stimulator of interferon genes protein External Id：CHEMBL5036846

实验名称：Induction of INF-gamma production in healthy human PBMC incubated for 16 hrs 来源：ChEMBL 靶标：N/A External Id：CHEMBL5036851

实验名称：Induction of INF-alpha production in healthy human PBMC incubated for 16 hrs 来源：ChEMBL 靶标：N/A External Id：CHEMBL5036849

实验名称：Activation of human STING REF mutant expressed in digitonin treated HEK293T cells co-... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5036839

实验名称：Activation of human STING HAQ mutant expressed in digitonin treated HEK293T cells co-... 来源：ChEMBL 靶标：Stimulator of interferon genes protein External Id：CHEMBL5036838

实验名称：Activation of wild-type human STING expressed in digitonin treated HEK293T cells co-e... 来源：ChEMBL 靶标：Stimulator of interferon genes protein External Id：CHEMBL5036837

共13条，当前第1页，共2页

1

2