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2-(4-methylpiperazin-1-yl)-1,3-benzoxazole

更新时间:2025-08-27 12:10:34

2-(4-methylpiperazin-1-yl)-1,3-benzoxazole结构式
2-(4-methylpiperazin-1-yl)-1,3-benzoxazole结构式
委托求购
常用名 2-(4-methylpiperazin-1-yl)-1,3-benzoxazole 英文名 2-(4-methylpiperazin-1-yl)-1,3-benzoxazole
CAS号 20128-05-6 分子量 217.26700
密度 N/A 沸点 N/A
分子式 C12H15N3O 熔点 N/A
MSDS N/A 闪点 N/A

 名称

英文名 2-(4-methylpiperazin-1-yl)-1,3-benzoxazole
英文别名 更多

 物理化学性质

分子式 C12H15N3O
分子量 217.26700
精确质量 217.12200
PSA 32.51000
LogP 1.58250
InChIKey AQDIORAYAFJBDK-UHFFFAOYSA-N
SMILES CN1CCN(c2nc3ccccc3o2)CC1

 合成线路

~90%

2-(4-methylpiperazin-1-yl)-1,3-benzoxazole结构式

2-(4-methylpipe...

20128-05-6

文献:Froehr, Tanja; Sindlinger, Christian P.; Kloeckner, Ulrich; Finkbeiner, Peter; Nachtsheim, Boris J. Organic Letters, 2011 , vol. 13, # 14 p. 3754 - 3757

~87%

2-(4-methylpiperazin-1-yl)-1,3-benzoxazole结构式

2-(4-methylpipe...

20128-05-6

文献:Srivastava, Vishnu P.; Yadav, Lal Dhar S. Synlett, 2013 , vol. 24, # 20 art. no. ST-2013-D0748-L, p. 2758 - 2762

~87%

2-(4-methylpiperazin-1-yl)-1,3-benzoxazole结构式

2-(4-methylpipe...

20128-05-6

文献:Murty; Ram, Kesur R.; Rao, Rayudu Venkateswara; Yadav Synthetic Communications, 2010 , vol. 40, # 19 p. 2844 - 2849

~%

2-(4-methylpiperazin-1-yl)-1,3-benzoxazole结构式

2-(4-methylpipe...

20128-05-6

文献:Murty; Ram, Kesur R.; Rao, Rayudu Venkateswara; Yadav; Rao, Janapala Venkateswara; Cheriyan, Vino T.; Anto, Ruby John Medicinal Chemistry Research, 2011 , vol. 20, # 5 p. 576 - 586

~%

2-(4-methylpiperazin-1-yl)-1,3-benzoxazole结构式

2-(4-methylpipe...

20128-05-6

文献:Murty; Ram, Kesur R.; Rao, Rayudu Venkateswara; Yadav; Kumar, K. Pranay Medicinal Chemistry Research, 2011 , vol. 20, # 5 p. 626 - 636 Title/Abstract Full Text View citing articles Show Details Murty; Ram, Kesur R.; Rao, Rayudu Venkateswara; Yadav; Rao, Janapala Venkateswara; Cheriyan, Vino T.; Anto, Ruby John Medicinal Chemistry Research, 2011 , vol. 20, # 5 p. 576 - 586

~%

2-(4-methylpiperazin-1-yl)-1,3-benzoxazole结构式

2-(4-methylpipe...

20128-05-6

文献:Yotphan, Sirilata; Beukeaw, Danupat; Reutrakul, Vichai Synthesis (Germany), 2013 , vol. 45, # 7 art. no. SS-2013-F0068-OP, p. 936 - 942

~%

2-(4-methylpiperazin-1-yl)-1,3-benzoxazole结构式

2-(4-methylpipe...

20128-05-6

文献:Yotphan, Sirilata; Beukeaw, Danupat; Reutrakul, Vichai Synthesis (Germany), 2013 , vol. 45, # 7 art. no. SS-2013-F0068-OP, p. 936 - 942

 靶点实验

查看更多实验

实验名称:Maximal partial agonist activity at 5-hydroxytryptamine 3 receptor of isolated guinea...
来源:ChEMBL
靶标:5-hydroxytryptamine receptor 3D
External Id:CHEMBL685647
实验名称:Primary cell-based high-throughput screening assay for identification of compounds th...
来源:Johns Hopkins Ion Channel Center
靶标:regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id:JHICC_RGS_Act_HTS
实验名称:Luminescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id:OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
实验名称:QFRET-based biochemical primary high throughput screening assay to identify exosite i...
来源:The Scripps Research Institute Molecular Screening Center
靶标:disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id:ADAM17_INH_QFRET_1536_1X%INH PRUN
实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_AG_FLUO8_1536_1X%ACT PRUN
实验名称:uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
来源:Burnham Center for Chemical Genomics
靶标:N/A
External Id:BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
实验名称:High throughput fluorescence intensity-based biochemical assay to screen for small mo...
来源:University of Pittsburgh Molecular Library Screening Center
靶标:furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id:MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
实验名称:Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
来源:Broad Institute
靶标:FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id:2147-01_Inhibitor_SinglePoint_HTS_Activity
实验名称:Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
来源:Broad Institute
靶标:N/A
External Id:Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify pos...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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 英文别名

hms2773m16
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