N-(3-Fluoropyridin-4-YL)-2-(6-methylpyridin-2-YL)-7H-pyrrolo[2,3-D]pyrimidin-4-amine

• 常用名: N-(3-Fluoropyridin-4-YL)-2-(6-methylpyridin-2-YL)-7H-pyrrolo[2,3-D]pyrimidin-4-amine
• 英文名: N-(3-Fluoropyridin-4-YL)-2-(6-methylpyridin-2-YL)-7H-pyrrolo[2,3-D]pyrimidin-4-amine
• CAS号: 2072050-95-2
• 分子量: 320.32
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₇H₁₃FN₆
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-(3-Fluoropyridin-4-YL)-2-(6-methylpyridin-2-YL)-7H-pyrrolo[2,3-D]pyrimidin-4-amine

物理化学性质

• 分子式: C₁₇H₁₃FN₆
• 分子量: 320.32
• InChIKey: GAWGUDTUQRRPQK-UHFFFAOYSA-N
• SMILES: Cc1cccc(-c2nc(Nc3ccncc3F)c3cc[nH]c3n2)n1

靶点实验

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实验名称：Inhibition of human His-tagged TGFbetaR1 T204D mutant expressed in Sf9 insect cells a... 来源：ChEMBL 靶标：TGF-beta receptor type-1 External Id：CHEMBL4188411

实验名称：Inhibition of wild type His-tagged TGFbetaR2 (unknown origin) after 1 hr by HTRF assa... 来源：ChEMBL 靶标：TGF-beta receptor type-2 External Id：CHEMBL4188412

实验名称：Biological Assays from US Patent US10399987: "TGF beta receptor antagonists" 来源：BindingDB 靶标：N/A External Id：BindingDB_8682_1

实验名称：Metabolic stability in human liver microsomes assessed as compound remaining by LC-MS... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4188413

实验名称：Metabolic stability in rat liver microsomes assessed as compound remaining by LC-MS/M... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4188414

实验名称：Metabolic stability in mouse liver microsomes assessed as compound remaining by LC-MS... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4188415

实验名称：Inhibition of TGFbetaR1 in mink Mv1Lu cells assessed as TGFbeta-stimulated PSMAD2 pho... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4188416

实验名称：Inhibition of TGFbetaR1 in human primary T-cells assessed as TGFbeta-stimulated PSMAD... 来源：ChEMBL 靶标：TGF-beta receptor type-1 External Id：CHEMBL4188417

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