(S)-3-([1,4'-Bipiperidin]-1'-ylmethyl)-N-(1-phenylethyl)-2-(3-(trifluoromethyl)phenyl)quinoline-4-carboxamide

• 常用名: (S)-3-([1,4'-Bipiperidin]-1'-ylmethyl)-N-(1-phenylethyl)-2-(3-(trifluoromethyl)phenyl)quinoline-4-carboxamide
• 英文名: (S)-3-([1,4'-Bipiperidin]-1'-ylmethyl)-N-(1-phenylethyl)-2-(3-(trifluoromethyl)phenyl)quinoline-4-carboxamide
• CAS号: 2095101-64-5
• 分子量: 600.7
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₆H₃₉F₃N₄O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (S)-3-([1,4'-Bipiperidin]-1'-ylmethyl)-N-(1-phenylethyl)-2-(3-(trifluoromethyl)phenyl)quinoline-4-carboxamide

物理化学性质

• 分子式: C₃₆H₃₉F₃N₄O
• 分子量: 600.7
• InChIKey: CPDKCWNAYYOWLG-VWLOTQADSA-N
• SMILES: CC(NC(=O)c1c(CN2CCC(N3CCCCC3)CC2)c(-c2cccc(C(F)(F)F)c2)nc2ccccc12)c1ccccc1

靶点实验

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实验名称：Dose normalized AUC in po dosed Sprague-Dawley rat 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3997714

实验名称：Selectivity ratio of IC50 for NK2 receptor (unknown origin) to IC50 for rat TRPV4 exp... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3997711

实验名称：Clearance in Sprague-Dawley rat 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3997710

实验名称：Toxicity in mouse isolated right atria assessed as effect on contractility 来源：ChEMBL 靶标：N/A External Id：CHEMBL3997742

实验名称：Oral bioavailability in Sprague-Dawley rat 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3997713

实验名称：Selectivity ratio of IC50 for NK3 receptor (unknown origin) to IC50 for rat TRPV4 exp... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3997712

实验名称：Toxicity in Beagle dog assessed as reduction in heart rate at 3 mg/kg, iv administere... 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL3997723

实验名称：Toxicity in Beagle dog assessed as reduction in BP at 3 mg/kg, iv administered as inf... 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL3997722

实验名称：Toxicity in Beagle dog assessed as effect on LV function at 3 mg/kg, iv administered ... 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL3997725

实验名称：Toxicity in Beagle dog assessed as effect on cardiac output at 3 mg/kg, iv administer... 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL3997724

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