N-cyclopropyl-6-((3,5-dimethylphenyl)amino)-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide

• 常用名: N-cyclopropyl-6-((3,5-dimethylphenyl)amino)-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide
• 英文名: N-cyclopropyl-6-((3,5-dimethylphenyl)amino)-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide
• CAS号: 2098468-04-1
• 分子量: 350.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₂₂N₆O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-cyclopropyl-6-((3,5-dimethylphenyl)amino)-8-(methylamino)imidazo[1,2-b]pyridazine-3-carboxamide

物理化学性质

• 分子式: C₁₉H₂₂N₆O
• 分子量: 350.4
• InChIKey: UNAWOCNJDJPOHK-UHFFFAOYSA-N
• SMILES: CNc1cc(Nc2cc(C)cc(C)c2)nn2c(C(=O)NC3CC3)cnc12

靶点实验

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实验名称：Displacement of [3H]-(R)-N-(1-(3-(8-methyl-5-(methylamino)-8H-imidazo[4,5-d]thiazolo[... 来源：ChEMBL 靶标：Non-receptor tyrosine-protein kinase TYK2 External Id：CHEMBL4251840

实验名称：Metabolic stability in mouse liver microsomes assessed as remaining parent compound a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4251846

实验名称：Metabolic stability in rat liver microsomes assessed as remaining parent compound at ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4251845

实验名称：Inhibition of TYK2 JH2 domain in IFNalpha-stimulated human Kit225 T cells by lucifera... 来源：ChEMBL 靶标：Non-receptor tyrosine-protein kinase TYK2 External Id：CHEMBL4251842

实验名称：Inhibition of TYK2 JH2 domain in IL23-stimulated human Kit225 T cells by luciferase r... 来源：ChEMBL 靶标：Non-receptor tyrosine-protein kinase TYK2 External Id：CHEMBL4251841

实验名称：Metabolic stability in human liver microsomes assessed as remaining parent compound a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4251844

实验名称：Displacement of [3H]-c-AMP from His-Tb-tagged human PDE4D2 (86 to 413 residues) prein... 来源：ChEMBL 靶标：cAMP-specific 3',5'-cyclic phosphodiesterase 4D External Id：CHEMBL4251843

实验名称：Inhibition of fluorescein-labeled kinase tracer binding to His-TVMV-fused TYK2 JH2 do... 来源：ChEMBL 靶标：Non-receptor tyrosine-protein kinase TYK2 External Id：CHEMBL4402444

实验名称：Inhibition of TYK2 JH2 domain in IFNalpha/IL23-stimulated human Kit225 cells by lucif... 来源：ChEMBL 靶标：Non-receptor tyrosine-protein kinase TYK2 External Id：CHEMBL4402445

实验名称：Inhibition of TYK2 JH2 domain in human whole blood assessed as decrease in IFNalpha/I... 来源：ChEMBL 靶标：Non-receptor tyrosine-protein kinase TYK2 External Id：CHEMBL4402446

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