1-[3-Cyano-5-(trifluoromethyl)phenyl]-3-[4-[4-(trifluoromethyl)phenoxy]cyclohexyl]urea

• 常用名: 1-[3-Cyano-5-(trifluoromethyl)phenyl]-3-[4-[4-(trifluoromethyl)phenoxy]cyclohexyl]urea
• 英文名: 1-[3-Cyano-5-(trifluoromethyl)phenyl]-3-[4-[4-(trifluoromethyl)phenoxy]cyclohexyl]urea
• CAS号: 2102097-05-0
• 分子量: 471.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₂H₁₉F₆N₃O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 1-[3-Cyano-5-(trifluoromethyl)phenyl]-3-[4-[4-(trifluoromethyl)phenoxy]cyclohexyl]urea

物理化学性质

• 分子式: C₂₂H₁₉F₆N₃O₂
• 分子量: 471.4
• InChIKey: PAFJUCOAUUKTIT-UHFFFAOYSA-N
• SMILES: N#Cc1cc(NC(=O)NC2CCC(Oc3ccc(C(F)(F)F)cc3)CC2)cc(C(F)(F)F)c1

靶点实验

查看更多实验

实验名称：Activation of eIF2alpha (unknown origin) assessed as fold stimulation ATF-4 surrogate... 来源：ChEMBL 靶标：Eukaryotic translation initiation factor 2 subunit 1 External Id：CHEMBL4707853

实验名称：Activation of eIF2alpha (unknown origin) assessed as fold stimulation ATF-4 surrogate... 来源：ChEMBL 靶标：Eukaryotic translation initiation factor 2 subunit 1 External Id：CHEMBL4707852

实验名称：Activation of eIF2alpha in human CRL-2813 cells assessed as eIF2alpha phosphorylation... 来源：ChEMBL 靶标：Eukaryotic translation initiation factor 2 subunit 1 External Id：CHEMBL4707855

实验名称：Antiproliferative activity against human CRL-2813 cells assessed as inhibition of cel... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4707854

实验名称：Activation of eIF2alpha in human CRL-2813 cells assessed as decrease in cyclin D1 exp... 来源：ChEMBL 靶标：Eukaryotic translation initiation factor 2 subunit 1 External Id：CHEMBL4707857

实验名称：Activation of eIF2alpha in human CRL-2813 cells assessed as increase in CHOP expressi... 来源：ChEMBL 靶标：Eukaryotic translation initiation factor 2 subunit 1 External Id：CHEMBL4707856

实验名称：Antiproliferative activity against human MCF7 cells transfected with HRI siRNA at 0.2... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL4707859

实验名称：Effect on p27Kip1 expression in human CRL-2813 cells at 5 uM measured after 8 hrs Wes... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4707858

实验名称：Tmax in NU008 nude mouse xenografted with human CRL2813 cells at 40 mg/kg, ip by LC-M... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4012861

实验名称：Apparent half life in NU008 nude mouse xenografted with human CRL2813 cells at 40 mg/... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4012862

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