谷氨酰胺酰基环化酶抑制剂1

• 常用名: 谷氨酰胺酰基环化酶抑制剂1
• 英文名: Glutaminyl Cyclase Inhibitor 1
• CAS号: 2110449-60-8
• 分子量: 369.43
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₂₄FN₃O₂
• 熔点: N/A
• 闪点: N/A

谷氨酰胺酰基环化酶抑制剂1用途

Glutaminyl Cyclase Inhibitor 1是谷氨酰胺酰基环化酶 (glutaminyl cyclase) 抑制剂,IC50 值为0.5 μM。

谷氨酰胺酰基环化酶抑制剂1名称

• 中文名: 谷氨酰胺酰基环化酶抑制剂1
• 英文名: Glutaminyl Cyclase Inhibitor 1

谷氨酰胺酰基环化酶抑制剂1生物活性

• 描述: Glutaminyl Cyclase Inhibitor 1是谷氨酰胺酰基环化酶 (glutaminyl cyclase) 抑制剂,IC50 值为0.5 μM。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 神经疾病
• 靶点实验:

  IC50: 0.5 μM (Glutaminyl cyclase)[1]

• 体外研究: 谷氨酰胺酰基环化酶抑制剂1是化合物23 [1]。
• 参考文献:

  [1]. Li M, et al. Synthesis and Evaluation of Diphenyl Conjugated Imidazole Derivatives as Potential Glutaminyl Cyclase Inhibitors for Treatment of Alzheimer's Disease. J Med Chem. 2017 Aug 10;60(15):6664-6677.

谷氨酰胺酰基环化酶抑制剂1物理化学性质

• 分子式: C₂₁H₂₄FN₃O₂
• 分子量: 369.43
• 储存条件: 2-8℃

谷氨酰胺酰基环化酶抑制剂1靶点实验

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实验名称：Direct cytotoxicity against human NCI-H1975 cells assessed as reduction in cell viabi... 来源：ChEMBL 靶标：NCI-H1975 External Id：CHEMBL5149906

实验名称：Inhibition of CD47/SIRPalpha interaction in human NCI-H1975 cells assessed as reducti... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5149907

实验名称：Inhibition of CD47/SIRPalpha interaction in human A549 cells assessed as reduction in... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5149908

实验名称：Inhibition of human N-terminal His6-tagged QC expressed in Escherichia coli BL21(DE3)... 来源：ChEMBL 靶标：Glutaminyl-peptide cyclotransferase External Id：CHEMBL4014210

实验名称：Induction of phagocytosis in CTFR labeled human NCI-H1975 cells co-cultured with PMA-... 来源：ChEMBL 靶标：NCI-H1975 External Id：CHEMBL5149918

实验名称：Direct cytotoxicity against human A549 cells assessed as reduction in cell viability ... 来源：ChEMBL 靶标：A549 External Id：CHEMBL5149903

实验名称：Induction of phagocytosis in CTFR labeled human A549 cells co-cultured with PMA-diffe... 来源：ChEMBL 靶标：A549 External Id：CHEMBL5149915

实验名称：Induction of phagocytosis in CTFR labeled human A549 cells co-cultured with PMA-diffe... 来源：ChEMBL 靶标：A549 External Id：CHEMBL5149916

实验名称：Induction of phagocytosis in CTFR labeled human NCI-H1975 cells co-cultured with PMA-... 来源：ChEMBL 靶标：NCI-H1975 External Id：CHEMBL5149917

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