1-(3,4-Dichloroanilino)-4-(4-pyridylmethyl)phthalazine

• 常用名: 1-(3,4-Dichloroanilino)-4-(4-pyridylmethyl)phthalazine
• 英文名: 1-(3,4-Dichloroanilino)-4-(4-pyridylmethyl)phthalazine
• CAS号: 212141-72-5
• 分子量: 381.3
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₁₄Cl₂N₄
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 1-(3,4-Dichloroanilino)-4-(4-pyridylmethyl)phthalazine

物理化学性质

• 分子式: C₂₀H₁₄Cl₂N₄
• 分子量: 381.3
• InChIKey: UIFQBRNVJVUAKO-UHFFFAOYSA-N
• SMILES: C1=CC=C2C(=C1)C(=NN=C2NC3=CC(=C(C=C3)Cl)Cl)CC4=CC=NC=C4

靶点实验

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实验名称：Inhibition of VEGF-stimulated autophosphorylation of VEGF-receptor 2 (KDR) expressed ... 来源：ChEMBL 靶标：Vascular endothelial growth factor receptor 2 External Id：CHEMBL818396

实验名称：The maximum concentration observed (Cmax) in the blood sample at indicated time point... 来源：ChEMBL 靶标：N/A External Id：CHEMBL632183

实验名称：PDGFR-beta Inhibition Assay from Article 10.1021/jm9909443: "New anilinophthalazines ... 来源：BindingDB 靶标：N/A External Id：BindingDB_656_2

实验名称：Inhibition of PDGF- beta receptor kinase 来源：ChEMBL 靶标：Platelet-derived growth factor receptor beta External Id：CHEMBL764645

实验名称：Kinase Inhibition Assay from Article 10.1021/jm9909443: "New anilinophthalazines as p... 来源：BindingDB 靶标：N/A External Id：BindingDB_656_1

实验名称：Inhibitory activity against kinase domain containing receptor (KDR/VEGFR2) 来源：ChEMBL 靶标：Vascular endothelial growth factor receptor 2 External Id：CHEMBL702231

实验名称：The maximum time reported (tmax) at an oral dose of 50 mg/Kg in mice 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL633503

实验名称：Inhibition of Proto-oncogene tyrosine-kinase c-Kit 来源：ChEMBL 靶标：Mast/stem cell growth factor receptor Kit External Id：CHEMBL769328

实验名称：Inhibitory activity against Flt-kinase 来源：ChEMBL 靶标：Vascular endothelial growth factor receptor 1 External Id：CHEMBL677134

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