CP-481715

• 常用名: CP-481715
• 英文名: CP-481715
• CAS号: 212790-31-3
• 分子量: 482.54700
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₆H₃₁FN₄O₄
• 熔点: N/A
• 闪点: N/A

CP-481715用途

CP-481715 is a potent and selective CCR1 antagonist with Ki of 9.2 nM and IC50 of 74 nM, lacks intrinsic agonist activity and .

CP-481715名称

• 英文名: N-[(2S,3S,5R)-5-carbamoyl-1-(3-fluorophenyl)-3,8-dihydroxy-8-methylnonan-2-yl]quinoxaline-2-carboxamide

CP-481715物理化学性质

• 分子式: C₂₆H₃₁FN₄O₄
• 分子量: 482.54700
• 精确质量: 482.23300
• PSA: 142.91000
• LogP: 4.23810
• InChIKey: YEQJVHQCUDMXFG-FHZYATBESA-N
• SMILES: CC(C)(O)CCC(CC(O)C(Cc1cccc(F)c1)NC(=O)c1cnc2ccccc2n1)C(N)=O

CP-481715靶点实验

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实验名称：Antagonist activity at recombinant CCR1 (unknown origin) expressed in non-adherent ce... 来源：ChEMBL 靶标：C-C chemokine receptor type 1 External Id：CHEMBL4371834

实验名称：Human CCR1 (Chemokine receptors) 来源：IUPHAR-DB 靶标：CCR1 (Chemokine receptors) [Homo sapiens] External Id：58_Human

实验名称：Antagonist activity at CCR1 in human THP1 cells assessed as inhibition of chemotaxis ... 来源：ChEMBL 靶标：C-C chemokine receptor type 1 External Id：CHEMBL4371835

实验名称：Binding affinity to CCR5 来源：ChEMBL 靶标：C-C chemokine receptor type 5 External Id：CHEMBL2184878

实验名称：Lipophilicity, log P of the compound 来源：ChEMBL 靶标：N/A External Id：CHEMBL2184882

实验名称：Binding affinity to CCR1 来源：ChEMBL 靶标：C-C chemokine receptor type 1 External Id：CHEMBL2184883

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CP-481715英文别名

• cp-481,715