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3-[[(2S)-azetidin-2-yl]methoxy]-5-iodopyridine

更新时间:2024-01-10 21:11:54

3-[[(2S)-azetidin-2-yl]methoxy]-5-iodopyridine结构式
3-[[(2S)-azetidin-2-yl]methoxy]-5-iodopyridine结构式
委托求购
常用名 3-[[(2S)-azetidin-2-yl]methoxy]-5-iodopyridine 英文名 3-[[(2S)-azetidin-2-yl]methoxy]-5-iodopyridine
CAS号 213550-82-4 分子量 290.10100
密度 N/A 沸点 N/A
分子式 C9H11IN2O 熔点 N/A
MSDS 中文版 美版 闪点 N/A

 名称

英文名 3-[[(2S)-azetidin-2-yl]methoxy]-5-iodopyridine
英文别名 更多

 物理化学性质

分子式 C9H11IN2O
分子量 290.10100
精确质量 289.99200
PSA 34.15000
LogP 1.75570

 文献2

更多文献
5-Iodo-A-85380, a specific ligand for alpha 4 beta 2 nicotinic acetylcholine receptors, prevents glutamate neurotoxicity in rat cortical cultured neurons.

Brain Res. 1199 , 46-52, (2008)

5-iodo-3-(2(S)-azetidinylmethoxy)pyridine (5-iodo-A-85380, 5IA) has very high affinity and selectivity to nicotinic acetylcholine receptor (nAChR) alpha 4 beta 2 subtype, and a relative safe profile. ...

Functional responses and subunit composition of presynaptic nicotinic receptor subtypes explored using the novel agonist 5-iodo-A-85380.

Neuropharmacology 47(6) , 848-59, (2004)

The novel compound 5-iodo-A-85380 binds with higher affinity to alpha4beta2* nicotinic acetylcholine receptors (nAChR), compared with other nAChR subtypes (Mukhin et al., 2000). In the present study, ...

 英文别名

Tocris-1518
5-Iodo-A-85380 dihydrochloride hydrate
Pyridine,3-((2S)-2-azetidinylmethoxy)-5-iodo
UNII-POX639L40H
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