2-(4-(2-diethylaminoethoxy)phenylamino)-8-ethyl-6-phenyl-8H-pyrido(2,3-d)pyrimidin-7-one

• 常用名: 2-(4-(2-diethylaminoethoxy)phenylamino)-8-ethyl-6-phenyl-8H-pyrido(2,3-d)pyrimidin-7-one
• 英文名: 2-(4-(2-diethylaminoethoxy)phenylamino)-8-ethyl-6-phenyl-8H-pyrido(2,3-d)pyrimidin-7-one
• CAS号: 214983-24-1
• 分子量: 457.6
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₇H₃₁N₅O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-(4-(2-diethylaminoethoxy)phenylamino)-8-ethyl-6-phenyl-8H-pyrido(2,3-d)pyrimidin-7-one

物理化学性质

• 分子式: C₂₇H₃₁N₅O₂
• 分子量: 457.6
• InChIKey: CUAUTGRQMYJPFC-UHFFFAOYSA-N
• SMILES: CCN1C2=NC(=NC=C2C=C(C1=O)C3=CC=CC=C3)NC4=CC=C(C=C4)OCCN(CC)CC

靶点实验

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实验名称：Inhibition against of platelet-derived growth factor receptor (PDGFr) 来源：ChEMBL 靶标：Platelet-derived growth factor receptor beta External Id：CHEMBL770314

实验名称：Compound was tested for apparent terminal phase elimination half life in three male W... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL639406

实验名称：Compound was tested for area under concentration -time curve from time 0 to time infi... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL622561

实验名称：Compound was tested for area under concentration -time curve from time 0 to time of l... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL622563

实验名称：Inhibition of recombinant RIPK2 (unknown origin) using RS repeat peptide as substrate... 来源：ChEMBL 靶标：Receptor-interacting serine/threonine-protein kinase 2 External Id：CHEMBL4815729

实验名称：Inhibition of PDGF-stimulated Platelet-derived growth factor receptor autophosphoryla... 来源：ChEMBL 靶标：Platelet-derived growth factor receptor beta External Id：CHEMBL770477

实验名称：Inhibition of human NOD2 expressed in HEK-blue cells coexpressing NFkappaB-SEAP repor... 来源：ChEMBL 靶标：Nucleotide-binding oligomerization domain-containing protein 2 External Id：CHEMBL4815730

实验名称：Inhibition of PDGF-stimulated Platelet-derived growth factor receptor autophosphoryla... 来源：ChEMBL 靶标：Platelet-derived growth factor receptor beta External Id：CHEMBL770474

实验名称：Inhibition of human ALK2 using casein as substrate incubated for 30 mins in presence ... 来源：ChEMBL 靶标：Activin receptor type-1 External Id：CHEMBL4815728

实验名称：Ratio of treated/control C6 glioma cell tumor mass at 40 mg/kg peroral dose, days 1-1... 来源：ChEMBL 靶标：C6 External Id：CHEMBL724868

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