dBRD9

• 常用名: dBRD9
• 英文名: dBRD9
• CAS号: 2170679-45-3
• 分子量: 783.839
• 密度: N/A
• 沸点: N/A
• 分子式: C₄₀H₄₅N₇O₁₀
• 熔点: N/A
• 闪点: N/A

dBRD9用途

dBRD9是桥接BRD9溴结构域和cereblon E3泛素连接酶复合物的PROTAC；与亲本配体相比表现出显着增强的效力(10-100倍)。

dBRD9名称

• 英文名: dBRD9

dBRD9生物活性

• 描述: dBRD9是桥接BRD9溴结构域和cereblon E3泛素连接酶复合物的PROTAC；与亲本配体相比表现出显着增强的效力(10-100倍)。
• 参考文献: References 1. Remillard D, et al. Angew Chem Int Ed Engl. 2017 May 15;56(21):5738-5743. View Related Products by Target PROTAC

dBRD9物理化学性质

• 分子式: C₄₀H₄₅N₇O₁₀
• 分子量: 783.839
• InChIKey: AIOCFZJGGGEWDK-UHFFFAOYSA-N
• SMILES: COc1cc(-c2cn(C)c(=O)c3cnccc23)cc(OC)c1CN(C)CC(=O)NCCOCCOCCNc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O

dBRD9靶点实验

查看更多实验

实验名称：Induction of BRD4 degradation in human G-401 cells at 0.1 nM incubated for 3 hrs by W... 来源：ChEMBL 靶标：Bromodomain-containing protein 4 External Id：CHEMBL5579207

实验名称：Induction of BRD4 degradation in human G-401 cells at 1 nM incubated for 3 hrs by Wes... 来源：ChEMBL 靶标：Bromodomain-containing protein 4 External Id：CHEMBL5579208

实验名称：Induction of BRD4 degradation in human G-401 cells at 10 nM incubated for 3 hrs by We... 来源：ChEMBL 靶标：Bromodomain-containing protein 4 External Id：CHEMBL5579209

实验名称：BRD9 Bromodomain TR-FRET Competition Binding Assay from US Patent US11773085: "Method... 来源：BindingDB 靶标：N/A External Id：BindingDB_11507_1

实验名称：Induction of BRD4 degradation in human G-401 cells at 100 nM incubated for 3 hrs by W... 来源：ChEMBL 靶标：Bromodomain-containing protein 4 External Id：CHEMBL5579210

实验名称：Induction of BRD4 degradation in human G-401 cells at 1000 nM incubated for 3 hrs by ... 来源：ChEMBL 靶标：Bromodomain-containing protein 4 External Id：CHEMBL5579211

实验名称：Induction of BRD7 degradation in human G-401 cells at 0.1 nM incubated for 3 hrs by W... 来源：ChEMBL 靶标：Bromodomain-containing protein 7 External Id：CHEMBL5579212

实验名称：Induction of BRD7 degradation in human G-401 cells at 1 nM incubated for 3 hrs by Wes... 来源：ChEMBL 靶标：Bromodomain-containing protein 7 External Id：CHEMBL5579213

实验名称：Induction of BRD7 degradation in human G-401 cells at 10 nM incubated for 3 hrs by We... 来源：ChEMBL 靶标：Bromodomain-containing protein 7 External Id：CHEMBL5579214

实验名称：Induction of BRD7 degradation in human G-401 cells at 100 nM incubated for 3 hrs by W... 来源：ChEMBL 靶标：Bromodomain-containing protein 7 External Id：CHEMBL5579215

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