顺式-1-氟-4-OTBS-环己烷用途
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Description The incorporation of fluorine in agrochemical and pharmaceutical compounds is of high interest due to the ability to fine-tune the polarity, pKA-value, conformation and metabolic stability. Derived from acis-selective hydrogenation developed by Glorius and coworkers, this fluorinated compound displays a diverse utility as a building block for chemical synthesis. Fluoro-cyclohexanol allows for the straightforward application in organic synthesis, after simple deprotection. It can be utilized to prepare fluorinated analogues of known compounds.
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