BMS-905

• 常用名: BMS-905
• 英文名: BMS-905
• CAS号: 2205846-49-5
• 分子量: 347.506
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₂₉N₃
• 熔点: N/A
• 闪点: N/A

BMS-905用途

BMS-905是TLR7和TLR8的有效双重抑制剂,IC50为0.3 nM(小鼠血液中的TLR7、IL-6抑制),对TLR9和其他TLR家族成员表现出良好的选择性。

BMS-905名称

• 英文名: BMS-905

BMS-905生物活性

• 描述: BMS-905是TLR7和TLR8的有效双重抑制剂,IC50为0.3 nM(小鼠血液中的TLR7、IL-6抑制),对TLR9和其他TLR家族成员表现出良好的选择性。
• 参考文献: 1. Ratna Kumar Sreekantha, et al. ACS Medicinal Chemistry Letters. DOI: 10.1021/acsmedchemlett.2c00049

BMS-905物理化学性质

• 分子式: C₂₃H₂₉N₃
• 分子量: 347.506
• InChIKey: XSXCQWXAFRASGU-UHFFFAOYSA-N
• SMILES: Cc1cc(-c2[nH]c3ccc(C4CCNCC4)cc3c2C(C)C)cc(C)n1

BMS-905靶点实验

查看更多实验

实验名称：Toxicity in MRL/Ipr Systemic lupus erythematosus mouse model assessed as relative spl... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5136044

实验名称：Toxicity in MRL/Ipr Systemic lupus erythematosus mouse model assessed as change in bo... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5136046

实验名称：Toxicity in MRL/Ipr Systemic lupus erythematosus mouse model assessed as relative spl... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5136041

实验名称：Toxicity in MRL/Ipr Systemic lupus erythematosus mouse model assessed as relative spl... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5136042

实验名称：Toxicity in MRL/Ipr Systemic lupus erythematosus mouse model assessed as relative spl... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5136043

实验名称：Anti-inflammatory activity against MRL/Ipr Systemic lupus erythematosus mouse model a... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5136037

实验名称：Anti-inflammatory activity against MRL/Ipr Systemic lupus erythematosus mouse model a... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5136038

实验名称：Anti-inflammatory activity against MRL/Ipr Systemic lupus erythematosus mouse model a... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5136039

实验名称：Anti-inflammatory activity against MRL/Ipr Systemic lupus erythematosus mouse model a... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5136032

实验名称：Anti-inflammatory activity against MRL/Ipr Systemic lupus erythematosus mouse model a... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL5136033

共43条，当前第1页，共5页

1

2

3

4

5