(S)-Cyclopropyl(3-((4-(6-hydroxy-2-(naphthalen-2-yl)-1H-benzo[d]imidazol-1-yl)pyrimidin-2-yl)amino)piperidin-1-yl)methanone

• 常用名: (S)-Cyclopropyl(3-((4-(6-hydroxy-2-(naphthalen-2-yl)-1H-benzo[d]imidazol-1-yl)pyrimidin-2-yl)amino)piperidin-1-yl)methanone
• 英文名: (S)-Cyclopropyl(3-((4-(6-hydroxy-2-(naphthalen-2-yl)-1H-benzo[d]imidazol-1-yl)pyrimidin-2-yl)amino)piperidin-1-yl)methanone
• CAS号: 2214258-36-1
• 分子量: 504.6
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₀H₂₈N₆O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (S)-Cyclopropyl(3-((4-(6-hydroxy-2-(naphthalen-2-yl)-1H-benzo[d]imidazol-1-yl)pyrimidin-2-yl)amino)piperidin-1-yl)methanone

物理化学性质

• 分子式: C₃₀H₂₈N₆O₂
• 分子量: 504.6
• InChIKey: GQWKCVUFYCHSLR-QHCPKHFHSA-N
• SMILES: O=C(C1CC1)N1CCCC(Nc2nccc(-n3c(-c4ccc5ccccc5c4)nc4ccc(O)cc43)n2)C1

靶点实验

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实验名称：Inhibition of p38alpha (unknown origin) at 1.0 uM preincubated for 20 mins followed b... 来源：ChEMBL 靶标：Mitogen-activated protein kinase 14 External Id：CHEMBL5340930

实验名称：Inhibition of FMS (unknown origin) at 1.0 uM preincubated for 20 mins followed by 33P... 来源：ChEMBL 靶标：Macrophage colony-stimulating factor 1 receptor External Id：CHEMBL5340929

实验名称：Effective permeability of compound by PAMPA-BBA method 来源：ChEMBL 靶标：N/A External Id：CHEMBL5340943

实验名称：AUC in sixteen hrs fasted Sprague-Dawley rat at 3 mg/kg, po measured upto 24 hrs by L... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5340924

实验名称：AUClast in sixteen hrs fasted Sprague-Dawley rat at 3 mg/kg, po measured upto 24 hrs ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5340936

实验名称：Neuroprotective activity against rat neuron cells assessed as inhibition of Abeta(1-4... 来源：ChEMBL 靶标：Neuron External Id：CHEMBL5340934

实验名称：Neuroprotective activity against rat neuron cells assessed as inhibition of Abeta(1-4... 来源：ChEMBL 靶标：Neuron External Id：CHEMBL5340935

实验名称：AUC in sixteen hrs fasted Sprague-Dawley rat at 1 mg/kg, iv measured upto 24 hrs by L... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5340983

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