3',4'-Difluoro-6-(((S)-pyrrolidin-3-yl)oxy)-N-(6-(((R)-pyrrolidin-3-yl)oxy)-3'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-3-yl)-[1,1'-biphenyl]-3-carboxamide dihydrochloride

• 常用名: 3',4'-Difluoro-6-(((S)-pyrrolidin-3-yl)oxy)-N-(6-(((R)-pyrrolidin-3-yl)oxy)-3'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-3-yl)-[1,1'-biphenyl]-3-carboxamide dihydrochloride
• 英文名: 3',4'-Difluoro-6-(((S)-pyrrolidin-3-yl)oxy)-N-(6-(((R)-pyrrolidin-3-yl)oxy)-3'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-3-yl)-[1,1'-biphenyl]-3-carboxamide dihydrochloride
• CAS号: 2226537-46-6
• 分子量: 696.6
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₄H₃₃Cl₂F₂N₇O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 3',4'-Difluoro-6-(((S)-pyrrolidin-3-yl)oxy)-N-(6-(((R)-pyrrolidin-3-yl)oxy)-3'-(2H-tetrazol-5-yl)-[1,1'-biphenyl]-3-yl)-[1,1'-biphenyl]-3-carboxamide dihydrochloride

物理化学性质

• 分子式: C₃₄H₃₃Cl₂F₂N₇O₃
• 分子量: 696.6
• InChIKey: FFEPHCHAWQYJQR-WDBMUBOCSA-N
• SMILES: C1CNC[C@H]1OC2=C(C=C(C=C2)C(=O)NC3=CC(=C(C=C3)O[C@@H]4CCNC4)C5=CC(=CC=C5)C6=NNN=N6)C7=CC(=C(C=C7)F)F.Cl.Cl

靶点实验

查看更多实验

实验名称：Cytotoxic activity in human SW480 cells at 800 uM incubated for 4 hrs by LDH release ... 来源：ChEMBL 靶标：SW480 External Id：CHEMBL4681825

实验名称：Drug level in human HCT-116 cells assessed as per million cells at 50 uM incubated fo... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4681874

实验名称：Selectivity index, ratio of Ki for inhibition of protein interaction between beta-cat... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4681810

实验名称：Drug level in human HCT-116 cells assessed as per million cells at 50 uM incubated fo... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4681869

实验名称：Inhibition of protein interaction between beta-catenin (unknown origin)/BCL9 in human... 来源：ChEMBL 靶标：B-cell CLL/lymphoma 9 protein External Id：CHEMBL4681809

实验名称：Drug level in human HCT-116 cells assessed as cell membrane bound compound level at 5... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4681873

实验名称：Effect on HPRT mRNA expression in human SW480 cells at 100 uM incubated for 24 hrs by... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4681859

实验名称：Effect on HPRT mRNA expression in human SW480 cells at 50 uM incubated for 24 hrs by ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4681858

实验名称：Inhibition of protein interaction between beta-catenin /BCL9 in human SW480 cells ass... 来源：ChEMBL 靶标：B-cell CLL/lymphoma 9 protein External Id：CHEMBL4681861

实验名称：Inhibition of protein interaction between beta-catenin /BCL9 in human SW480 cells ass... 来源：ChEMBL 靶标：B-cell CLL/lymphoma 9 protein External Id：CHEMBL4681860

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