[3-[[5-Methyl-2-[[3-(4-methylpiperazin-1-yl)-5-methylsulfonyl-phenyl]amino]pyrimidin-4-yl]amino]phenyl]methanol

• 常用名: [3-[[5-Methyl-2-[[3-(4-methylpiperazin-1-yl)-5-methylsulfonyl-phenyl]amino]pyrimidin-4-yl]amino]phenyl]methanol
• 英文名: [3-[[5-Methyl-2-[[3-(4-methylpiperazin-1-yl)-5-methylsulfonyl-phenyl]amino]pyrimidin-4-yl]amino]phenyl]methanol
• CAS号: 2228908-74-3
• 分子量: 482.6
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₄H₃₀N₆O₃S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: [3-[[5-Methyl-2-[[3-(4-methylpiperazin-1-yl)-5-methylsulfonyl-phenyl]amino]pyrimidin-4-yl]amino]phenyl]methanol

物理化学性质

• 分子式: C₂₄H₃₀N₆O₃S
• 分子量: 482.6
• InChIKey: WKJVLTJTBZVAKC-UHFFFAOYSA-N
• SMILES: Cc1cnc(Nc2cc(N3CCN(C)CC3)cc(S(C)(=O)=O)c2)nc1Nc1cccc(CO)c1

靶点实验

查看更多实验

实验名称：Inhibition of cytoplasmic recombinant human GST-tagged JAK1 (886 to 1154 residues) ex... 来源：ChEMBL 靶标：Tyrosine-protein kinase JAK1 External Id：CHEMBL4145183

实验名称：Inhibition of recombinant human JAK2 (831 to 1132 residues) expressed in insect cells... 来源：ChEMBL 靶标：Tyrosine-protein kinase JAK2 External Id：CHEMBL4145184

实验名称：Inhibition of recombinant human JAK3 (781 to 1124 residues) expressed in insect cells... 来源：ChEMBL 靶标：Tyrosine-protein kinase JAK3 External Id：CHEMBL4145185

实验名称：Selectivity ratio of IC50 for recombinant human JAK2 (831 to 1132 residues) expressed... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4145186

实验名称：Octanol-water partition coefficient, log D of the compound in sodium phosphate buffer... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4145187

实验名称：Inhibition of JAK1 in human NCI-H1975 cells assessed as reduction in STAT3 phosphoryl... 来源：ChEMBL 靶标：Tyrosine-protein kinase JAK1 External Id：CHEMBL4145188

实验名称：Intrinsic clearance in human liver microsomes 来源：ChEMBL 靶标：N/A External Id：CHEMBL4145189

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