2-(4-fluoro-3-(trifluoromethyl)phenyl)-N-(5-fluoropyridin-2-yl)-3H-imidazo[4,5-c]pyridin-6-amine

• 常用名: 2-(4-fluoro-3-(trifluoromethyl)phenyl)-N-(5-fluoropyridin-2-yl)-3H-imidazo[4,5-c]pyridin-6-amine
• 英文名: 2-(4-fluoro-3-(trifluoromethyl)phenyl)-N-(5-fluoropyridin-2-yl)-3H-imidazo[4,5-c]pyridin-6-amine
• CAS号: 2229042-83-3
• 分子量: 391.3
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₁₀F₅N₅
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-(4-fluoro-3-(trifluoromethyl)phenyl)-N-(5-fluoropyridin-2-yl)-3H-imidazo[4,5-c]pyridin-6-amine

物理化学性质

• 分子式: C₁₈H₁₀F₅N₅
• 分子量: 391.3
• InChIKey: JRSFNNQMJGDBNA-UHFFFAOYSA-N
• SMILES: Fc1ccc(Nc2cc3nc(-c4ccc(F)c(C(F)(F)F)c4)[nH]c3cn2)nc1

靶点实验

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实验名称：Dose normalized AUC (0 to infinity) in Sprague-Dawley rat at 20 mg/kg administered vi... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL4189419

实验名称：Dose normalized AUC (0 to infinity) in Sprague-Dawley rat at 5 mg/kg, iv administered... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL4189420

实验名称：Tmax in Sprague-Dawley rat at 20 mg/kg administered via oral gavage as bolus dose by ... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL4189415

实验名称：Tmax in BALB/c mouse at 10 mg/kg administered via oral gavage as bolus dose by LC-MS/... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4189417

实验名称：Antimalarial activity against Plasmodium falciparum 3D7 infected in NOD-scid IL-2Rgam... 来源：ChEMBL 靶标：Plasmodium falciparum External Id：CHEMBL4189429

实验名称：Antimalarial activity against Plasmodium falciparum 3D7 infected in NOD-scid IL-2Rgam... 来源：ChEMBL 靶标：Plasmodium falciparum External Id：CHEMBL4189430

实验名称：Dose normalized AUC (0 to infinity) in BALB/c mouse at 10 mg/kg administered via oral... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4189423

实验名称：Oral bioavailability in Sprague-Dawley rat at 20 mg/kg administered via gavage as bol... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL4189426

实验名称：Volume of distribution in Sprague-Dawley rat at 5 mg/kg, iv administered as 2 mins of... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL4189405

实验名称：Elimination half life in BALB/c mouse at 10 mg/kg administered via oral gavage as bol... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4189399

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