2-(4,4-difluorocyclohexyl)-N-(5-(trifluoromethyl)pyridin-2-yl)-3H-imidazo[4,5-c]pyridin-6-amine

• 常用名: 2-(4,4-difluorocyclohexyl)-N-(5-(trifluoromethyl)pyridin-2-yl)-3H-imidazo[4,5-c]pyridin-6-amine
• 英文名: 2-(4,4-difluorocyclohexyl)-N-(5-(trifluoromethyl)pyridin-2-yl)-3H-imidazo[4,5-c]pyridin-6-amine
• CAS号: 2229050-97-7
• 分子量: 397.3
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₁₆F₅N₅
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-(4,4-difluorocyclohexyl)-N-(5-(trifluoromethyl)pyridin-2-yl)-3H-imidazo[4,5-c]pyridin-6-amine

物理化学性质

• 分子式: C₁₈H₁₆F₅N₅
• 分子量: 397.3
• InChIKey: ATKFWGWSXHYEQL-UHFFFAOYSA-N
• SMILES: FC1(F)CCC(c2nc3cc(Nc4ccc(C(F)(F)F)cn4)ncc3[nH]2)CC1

靶点实验

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实验名称：Dose normalized AUC (0 to 23 hrs) in NOD-scid IL-2Rgamma-null mouse model engrafted w... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4189355

实验名称：Dose normalized AUC (0 to infinity) in Sprague-Dawley rat at 15 mg/kg administered vi... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL4189421

实验名称：Dose normalized AUC (0 to infinity) in Sprague-Dawley rat at 3 mg/kg, iv administered... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL4189422

实验名称：Tmax in Sprague-Dawley rat at 15 mg/kg administered via oral gavage as bolus dose by ... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL4189416

实验名称：Tmax in BALB/c mouse at 20 mg/kg administered via oral gavage as bolus dose by LC-MS/... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4189418

实验名称：Oral bioavailability in Sprague-Dawley rat at 15 mg/kg administered via gavage as bol... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL4189427

实验名称：Oral bioavailability in BALB/c mouse at 20 mg/kg administered via gavage as bolus dos... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4189428

实验名称：Antimalarial activity against Plasmodium falciparum 3D7 infected in NOD-scid IL-2Rgam... 来源：ChEMBL 靶标：Plasmodium falciparum External Id：CHEMBL4189429

实验名称：Antimalarial activity against Plasmodium falciparum 3D7 infected in NOD-scid IL-2Rgam... 来源：ChEMBL 靶标：Plasmodium falciparum External Id：CHEMBL4189430

实验名称：Metabolic stability in mouse liver microsomes assessed as parent compound remaining a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4189366

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