4-Pyrimidinamine,N-[5-(3-fluorophenyl)-1H-pyrazol-3-yl]-6-(4-methyl-1-piperazinyl)-2-(phenylthio)

• 常用名: 4-Pyrimidinamine,N-[5-(3-fluorophenyl)-1H-pyrazol-3-yl]-6-(4-methyl-1-piperazinyl)-2-(phenylthio)
• 英文名: 4-Pyrimidinamine,N-[5-(3-fluorophenyl)-1H-pyrazol-3-yl]-6-(4-methyl-1-piperazinyl)-2-(phenylthio)
• CAS号: 2231038-82-5
• 分子量: 461.6
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₄H₂₄FN₇S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 4-Pyrimidinamine,N-[5-(3-fluorophenyl)-1H-pyrazol-3-yl]-6-(4-methyl-1-piperazinyl)-2-(phenylthio)

物理化学性质

• 分子式: C₂₄H₂₄FN₇S
• 分子量: 461.6
• InChIKey: NIYBCVRMZHPXIV-UHFFFAOYSA-N
• SMILES: CN1CCN(c2cc(Nc3cc(-c4cccc(F)c4)[nH]n3)nc(Sc3ccccc3)n2)CC1

靶点实验

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实验名称：Inhibition of DNA-tagged human partial length JAK3 JH1 domain-catalytic expressed in ... 来源：ChEMBL 靶标：Tyrosine-protein kinase JAK3 External Id：CHEMBL4189915

实验名称：Inhibition of DNA-tagged human phosphorylated partial length ABL1 T315I mutant expres... 来源：ChEMBL 靶标：Tyrosine-protein kinase ABL1 External Id：CHEMBL4189916

实验名称：Inhibition of DNA-tagged human nonphosphorylated partial length ABL1 expressed in mam... 来源：ChEMBL 靶标：Tyrosine-protein kinase ABL1 External Id：CHEMBL4189917

实验名称：Selectivity ratio of Kd for DNA-tagged human partial length AURKA to Kd for DNA-tagge... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4189918

实验名称：Inhibition of DNA-tagged human partial length PDGFRB expressed in mammalian expressio... 来源：ChEMBL 靶标：Platelet-derived growth factor receptor beta External Id：CHEMBL4189911

实验名称：Inhibition of DNA-tagged human partial length RET expressed in bacterial expression s... 来源：ChEMBL 靶标：Proto-oncogene tyrosine-protein kinase receptor Ret External Id：CHEMBL4189912

实验名称：Inhibition of DNA-tagged human partial length TrkA expressed in mammalian expression ... 来源：ChEMBL 靶标：High affinity nerve growth factor receptor External Id：CHEMBL4189913

实验名称：Inhibition of DNA-tagged human partial length JAK2 JH1 domain-catalytic expressed in ... 来源：ChEMBL 靶标：Tyrosine-protein kinase JAK2 External Id：CHEMBL4189914

实验名称：Inhibition of DNA-tagged human partial length TrkB expressed in mammalian expression ... 来源：ChEMBL 靶标：BDNF/NT-3 growth factors receptor External Id：CHEMBL4189907

实验名称：Inhibition of DNA-tagged human partial length TrkC expressed in mammalian expression ... 来源：ChEMBL 靶标：NT-3 growth factor receptor External Id：CHEMBL4189908

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