5-(4-Chlorophenyl)-7-|A-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

• 常用名: 5-(4-Chlorophenyl)-7-|A-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• 英文名: 5-(4-Chlorophenyl)-7-|A-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine
• CAS号: 2257426-61-0
• 分子量: 376.8
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₇H₁₇ClN₄O₄
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 5-(4-Chlorophenyl)-7-|A-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

物理化学性质

• 分子式: C₁₇H₁₇ClN₄O₄
• 分子量: 376.8
• InChIKey: KTFHCMFKCRSHAI-LSCFUAHRSA-N
• SMILES: C1=CC(=CC=C1C2=CN(C3=NC=NC(=C23)N)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O)Cl

靶点实验

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实验名称：Drug metabolism in human liver microsome S9 fraction assessed as CYP450-mediated meta... 来源：ChEMBL 靶标：Cytochrome P450 2C19 External Id：CHEMBL4383192

实验名称：Therapeutic index, ratio EC50 for human MRC5 SV2 cells to EC50 for Trypanosoma cruzi ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4383193

实验名称：Antiparasitic activity against Trypanosoma cruzi Tulahuen CL2 intracellular amastigot... 来源：ChEMBL 靶标：Trypanosoma cruzi External Id：CHEMBL4383194

实验名称：Cytotoxicity against human MRC5 SV2 cells assessed as reduction in cell viability aft... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4383195

实验名称：Drug metabolism in mouse liver microsome S9 fraction assessed as CYP450-mediated meta... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4383196

实验名称：Drug metabolism in mouse liver microsome S9 fraction assessed as CYP450-mediated meta... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4383197

实验名称：Potency index, ratio of EC50 for benznidazole to EC50 for test compound for antitrypa... 来源：ChEMBL 靶标：Trypanosoma cruzi External Id：CHEMBL4424090

实验名称：Antiparasitic activity against Trypanosoma cruzi Y strain bloodstream trypomastigotes... 来源：ChEMBL 靶标：Trypanosoma cruzi External Id：CHEMBL4383231

实验名称：Antitrypanosomal activity against nifurtimox-sensitive Trypanosoma cruzi Tulahuen CL2... 来源：ChEMBL 靶标：Trypanosoma cruzi External Id：CHEMBL4424084

实验名称：Selectivity index, ratio of EC50 for human MRC5 cells to EC50 for nifurtimox-sensitiv... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4424085

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