2,4-difluoro-N-[5-[4-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]quinazolin-6-yl]-2-methoxy-3-pyridinyl]benzenesulfonamide

• 常用名: 2,4-difluoro-N-[5-[4-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]quinazolin-6-yl]-2-methoxy-3-pyridinyl]benzenesulfonamide
• 英文名: 2,4-difluoro-N-[5-[4-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]quinazolin-6-yl]-2-methoxy-3-pyridinyl]benzenesulfonamide
• CAS号: 2269470-35-9
• 分子量: 553.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₅H₂₁F₂N₇O₄S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2,4-difluoro-N-[5-[4-[[1-(2-hydroxyethyl)pyrazol-4-yl]amino]quinazolin-6-yl]-2-methoxy-3-pyridinyl]benzenesulfonamide

物理化学性质

• 分子式: C₂₅H₂₁F₂N₇O₄S
• 分子量: 553.5
• InChIKey: DUUVJFLCJKWQTO-UHFFFAOYSA-N
• SMILES: COC1=C(C=C(C=N1)C2=CC3=C(C=C2)N=CN=C3NC4=CN(N=C4)CCO)NS(=O)(=O)C5=C(C=C(C=C5)F)F

靶点实验

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实验名称：Induction of apoptosis in human MCF7 cells assessed as chromatin condensation at 0.2 ... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL4667337

实验名称：Induction of apoptosis in human MCF7 cells assessed as necrotic cells at 0.8 uM incub... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL4667339

实验名称：Induction of apoptosis in human MCF7 cells assessed as nuclear fragmentation at 0.2 t... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL4667338

实验名称：Induction of apoptosis in human MCF7 cells assessed as necrotic cells at 0.2 uM incub... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL4667341

实验名称：Induction of apoptosis in human MCF7 cells assessed as necrotic cells at 0.4 uM incub... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL4667340

实验名称：Induction of apoptosis in human MCF7 cells assessed as late apoptotic cells at 0.4 uM... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL4667343

实验名称：Induction of apoptosis in human MCF7 cells assessed as late apoptotic cells at 0.8 uM... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL4667342

实验名称：Antitumor activity against human T47D cells xenografted in nude BALB/c mouse assessed... 来源：ChEMBL 靶标：T47D External Id：CHEMBL5620689

实验名称：Antitumor activity against human T47D cells xenografted in nude BALB/c mouse assessed... 来源：ChEMBL 靶标：T47D External Id：CHEMBL5620690

实验名称：Inhibition of PI3K in human MCF7 cells assessed as Akt phosphorylation by Western blo... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4667353

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