N-{3-[5-(4-chlorophenyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide

• 常用名: N-{3-[5-(4-chlorophenyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide
• 英文名: N-{3-[5-(4-chlorophenyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide
• CAS号: 2274779-58-5
• 分子量: 490.9
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₂H₁₇ClF₂N₄O₃S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-{3-[5-(4-chlorophenyl)-1H-pyrazolo[3,4-b]pyridine-3-carbonyl]-2,4-difluorophenyl}propane-1-sulfonamide

物理化学性质

• 分子式: C₂₂H₁₇ClF₂N₄O₃S
• 分子量: 490.9
• InChIKey: BDNQEZGZWYFOSD-UHFFFAOYSA-N
• SMILES: CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2[nH]nc3ncc(-c4ccc(Cl)cc4)cc23)c1F

靶点实验

查看更多实验

实验名称：Selectivity index, ratio of inhibition of full length human MKK7 (M1 to R419 residues... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4742622

实验名称：Selectivity index, ratio of inhibition of B-raf (unknown origin) to inhibition of par... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4742623

实验名称：Inhibition of partial length human MKK4 (S84 to D399 residues) expressed in mammalian... 来源：ChEMBL 靶标：Dual specificity mitogen-activated protein kinase kinase 4 External Id：CHEMBL4742620

实验名称：Selectivity index, ratio of inhibition of full length human JNK1 (M1 to Q384 residues... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4742621

实验名称：Inhibition of MEKK2 (unknown origin) using casein as substrate in presence of [gamma-... 来源：ChEMBL 靶标：Dual specificity mitogen-activated protein kinase kinase 4 External Id：CHEMBL4742626

实验名称：Inhibition of MEKK2- induced activation of MKK4/(unknown origin) using JNK1 as substr... 来源：ChEMBL 靶标：Dual specificity mitogen-activated protein kinase kinase 4 External Id：CHEMBL4742624

实验名称：Inhibition of MKK4/(unknown origin) using JNK1 as substrate in presence of [gamma-33P... 来源：ChEMBL 靶标：Dual specificity mitogen-activated protein kinase kinase 4 External Id：CHEMBL4742625

实验名称：Binding affinity to wild-type human partial length MKK4 (S84 to D399 residues) expres... 来源：ChEMBL 靶标：Dual specificity mitogen-activated protein kinase kinase 4 External Id：CHEMBL4812261

实验名称：Binding affinity to MKK4 (unknown origin) assessed as percent of control at 100 nM by... 来源：ChEMBL 靶标：Dual specificity mitogen-activated protein kinase kinase 4 External Id：CHEMBL5118602

实验名称：Binding affinity to wild-type human full length MKK7 (M1 to R419 residues) expressed ... 来源：ChEMBL 靶标：Dual specificity mitogen-activated protein kinase kinase 7 External Id：CHEMBL4812262

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