DO-264

• 常用名: DO-264
• 英文名: DO-264
• CAS号: 2301866-59-9
• 分子量: 558.403
• 密度: 1.5±0.1 g/cm3
• 沸点: 601.5±65.0 °C at 760 mmHg
• 分子式: C₂₃H₂₀Cl₂F₃N₅O₂S
• 熔点: N/A
• 闪点: 317.6±34.3 °C

DO-264用途

DO264 is an inhibitor of α/β-hydrolase domain-containing protein 12 (ABHD12; IC50 = 11 nM).It inhibits ABHD12-dependent hydrolysis of lysophosphatidylserine (lyso-PS) in mouse brain membrane lysates (IC50 = 2.8 nM) and human THP-1 cells.

DO-264名称

• 英文名: 1-(1-{3-Chloro-4-[2-chloro-4-(trifluoromethoxy)phenoxy]-2-pyridinyl}-4-piperidinyl)-3-(3-pyridinyl)thiourea

DO-264物理化学性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 601.5±65.0 °C at 760 mmHg
• 分子式: C₂₃H₂₀Cl₂F₃N₅O₂S
• 分子量: 558.403
• 闪点: 317.6±34.3 °C
• 精确质量: 557.066711
• LogP: 5.44
• 蒸汽压: 0.0±1.7 mmHg at 25°C
• 折射率: 1.653

DO-264英文别名

• Thiourea, N-[1-[3-chloro-4-[2-chloro-4-(trifluoromethoxy)phenoxy]-2-pyridinyl]-4-piperidinyl]-N'-3-pyridinyl-
• 1-(1-{3-Chloro-4-[2-chloro-4-(trifluoromethoxy)phenoxy]-2-pyridinyl}-4-piperidinyl)-3-(3-pyridinyl)thiourea