(R)-1-(2-((2-Methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide

• 常用名: (R)-1-(2-((2-Methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide
• 英文名: (R)-1-(2-((2-Methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide
• CAS号: 2365497-12-5
• 分子量: 584.6
• 密度: N/A
• 沸点: N/A
• 分子式: C₃₀H₃₅F₃N₆O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (R)-1-(2-((2-Methoxy-4-(piperazin-1-yl)phenyl)amino)pyridin-4-yl)-N-(4-(trifluoromethoxy)benzyl)piperidine-3-carboxamide

物理化学性质

• 分子式: C₃₀H₃₅F₃N₆O₃
• 分子量: 584.6
• InChIKey: JQWJRFOFKDLCQB-JOCHJYFZSA-N
• SMILES: COc1cc(N2CCNCC2)ccc1Nc1cc(N2CCCC(C(=O)NCc3ccc(OC(F)(F)F)cc3)C2)ccn1

靶点实验

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实验名称：Antiproliferative activity against ROS1-addicted human HCC78 cells assessed as reduct... 来源：ChEMBL 靶标：HCC78 External Id：CHEMBL4354250

实验名称：Antiproliferative activity against ALK-addicted human NCI-H3122 cells assessed as red... 来源：ChEMBL 靶标：NCI-H3122 External Id：CHEMBL4354249

实验名称：Antiproliferative activity against human A549 cells assessed as reduction in cell via... 来源：ChEMBL 靶标：A549 External Id：CHEMBL4354248

实验名称：Inhibition of recombinant human N-terminal GST-tagged ROS1 (catalytic domain 1883 - 2... 来源：ChEMBL 靶标：Proto-oncogene tyrosine-protein kinase ROS External Id：CHEMBL4354247

实验名称：Inhibition of recombinant human N-terminal GST-tagged ALK (catalytic domain 1058 - 16... 来源：ChEMBL 靶标：ALK tyrosine kinase receptor External Id：CHEMBL4354246

实验名称：Inhibition of recombinant human N-terminal GST-tagged ALK (catalytic domain 1058 - 16... 来源：ChEMBL 靶标：ALK tyrosine kinase receptor External Id：CHEMBL4354245

实验名称：Inhibition of recombinant human N-terminal GST-tagged ROS1 (catalytic domain 1883 - 2... 来源：ChEMBL 靶标：Proto-oncogene tyrosine-protein kinase ROS External Id：CHEMBL4354244

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