Shp2-IN-27

• 常用名: Shp2-IN-27
• 英文名: Shp2-IN-27
• CAS号: 2376012-00-7
• 分子量: 407.9
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₂₂ClN₇
• 熔点: N/A
• 闪点: N/A

Shp2-IN-27名称

• 英文名: Shp2-IN-27

Shp2-IN-27物理化学性质

• 分子式: C₂₁H₂₂ClN₇
• 分子量: 407.9
• InChIKey: XRNTZAQBJAFMBB-YHWZYXNKSA-N
• SMILES: CN1C=C2C(=N1)C=CC(=C2Cl)C3=CNC4=NC(=CN=C34)N5[C@@H]6CC[C@H]5CC(C6)N

Shp2-IN-27靶点实验

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实验名称：Half life in BALB/c mouse at 5 mg/kg, po administered as single dose via nasogastric ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5521320

实验名称：AUC in BALB/c mouse at 5 mg/kg, po administered as single dose via nasogastric gavage... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5521319

实验名称：Volume of distribution at steady state in BALB/c mouse at 5 mg/kg, iv administered vi... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5521318

实验名称：Clearance in BALB/c mouse at 5 mg/kg, iv administered via lateral tail vein by HPLC-M... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5521317

实验名称：Efflux ratio of permeability across basolateral to apical side over apical to basolat... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5521316

实验名称：Permeability across apical to basolateral side in human Caco-2 cells at 10 uM incubat... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5521315

实验名称：Metabolic stability in CD-1 mouse liver microsomes assessed as half life at 1 uM incu... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5521314

实验名称：Antiproliferative activity against human HCC827 cells harboring EGFR del 746 to 750 m... 来源：ChEMBL 靶标：HCC827 External Id：CHEMBL5521313

实验名称：Inhibition of SHP2 in human HCC827 cells harboring EGFR del 746 to 750 mutant assesse... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 11 External Id：CHEMBL5521312

实验名称：Chromatographic log D of compound at pH 7.4 by RP-HPLC analysis 来源：ChEMBL 靶标：N/A External Id：CHEMBL5521311

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