6,8-difluoro-3-(2-methylpropanoyl)-2-(2,3,4-trifluoroanilino)-1H-quinolin-4-one

• 常用名: 6,8-difluoro-3-(2-methylpropanoyl)-2-(2,3,4-trifluoroanilino)-1H-quinolin-4-one
• 英文名: 6,8-difluoro-3-(2-methylpropanoyl)-2-(2,3,4-trifluoroanilino)-1H-quinolin-4-one
• CAS号: 2379890-92-1
• 分子量: 396.3
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₁₃F₅N₂O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 6,8-difluoro-3-(2-methylpropanoyl)-2-(2,3,4-trifluoroanilino)-1H-quinolin-4-one

物理化学性质

• 分子式: C₁₉H₁₃F₅N₂O₂
• 分子量: 396.3
• InChIKey: DMIXYWAIQQRKNT-UHFFFAOYSA-N
• SMILES: CC(C)C(=O)C1=C(NC2=C(C1=O)C=C(C=C2F)F)NC3=C(C(=C(C=C3)F)F)F

靶点实验

查看更多实验

实验名称：Metabolic stability in rat microsomes assessed as parent compound remaining measured ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4315148

实验名称：Metabolic stability in human microsomes assessed as parent compound remaining measure... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4315147

实验名称：Selectivity index, ratio of CC50 for African green monkey Vero cells to IC50 for MERS... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4315146

实验名称：Cytotoxicity against African green monkey Vero cells assessed as reduction in cell vi... 来源：ChEMBL 靶标：Vero External Id：CHEMBL4315145

实验名称：Antiviral activity against MERS-CoV KOR/KNIH/002_05_2015 infected in African green mo... 来源：ChEMBL 靶标：Middle East respiratory syndrome-related coronavirus External Id：CHEMBL4315144

实验名称：Oral bioavailability in rat at 5 mg/kg 来源：ChEMBL 靶标：N/A External Id：CHEMBL4315160

实验名称：Clearance in rat at 2 mg/kg, iv 来源：ChEMBL 靶标：N/A External Id：CHEMBL4315159

实验名称：AUC (0 to infinity) in rat at 2 mg/kg, iv 来源：ChEMBL 靶标：N/A External Id：CHEMBL4315158

实验名称：AUC (0 to 24 hrs) in rat at 2 mg/kg, iv 来源：ChEMBL 靶标：N/A External Id：CHEMBL4315157

实验名称：Half life in rat at 2 mg/kg, iv 来源：ChEMBL 靶标：N/A External Id：CHEMBL4315156

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