N-Methyl-4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine

• 常用名: N-Methyl-4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine
• 英文名: N-Methyl-4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine
• CAS号: 2408831-67-2
• 分子量: 226.24
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₁H₁₀N₆
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-Methyl-4-(pyrazolo[1,5-b]pyridazin-3-yl)pyrimidin-2-amine

物理化学性质

• 分子式: C₁₁H₁₀N₆
• 分子量: 226.24
• InChIKey: AXNJRTBQYGIJON-UHFFFAOYSA-N
• SMILES: CNc1nccc(-c2cnn3ncccc23)n1

靶点实验

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实验名称：Cytotoxicity against human MRC5 cells assessed as reduction in cell viability after 4... 来源：ChEMBL 靶标：MRC5 External Id：CHEMBL4325183

实验名称：Protein binding in human plasma after 18 hrs by LC/MS/MS based rapid equilibrium dial... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4325182

实验名称：Intrinsic clearance in human liver microsomes assessed per mg protein by LC/MS/MS ana... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4325181

实验名称：Intrinsic clearance in Han Wistar rat hepatocytes assessed per million cells at 1 uM ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4325180

实验名称：1-Octanol-aquoues buffer distribution coefficient, log D of compound at pH 7.4 by UPL... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4325179

实验名称：Displacement of Kinase tracer 236 from biotinylated DYRK1A (unknown origin) expressed... 来源：ChEMBL 靶标：Dual specificity tyrosine-phosphorylation-regulated kinase 1A External Id：CHEMBL4810626

实验名称：Thermodynamic aqueous solubility of compound in phosphate buffer at pH 7.4 incubated ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4325178

实验名称：Binding affinity to biotinylated DYRK1A (unknown origin) expressed in Escherichia col... 来源：ChEMBL 靶标：Dual specificity tyrosine-phosphorylation-regulated kinase 1A External Id：CHEMBL4810627

实验名称：Antitrypanosomal activity against Trypanosoma brucei brucei Lister 427 blood stream f... 来源：ChEMBL 靶标：Trypanosoma brucei brucei External Id：CHEMBL4325174

实验名称：Binding affinity to biotinylated DYRK1A (unknown origin) expressed in Escherichia col... 来源：ChEMBL 靶标：Dual specificity tyrosine-phosphorylation-regulated kinase 1A External Id：CHEMBL4810628

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