(R)-N-(5-((S)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide

• 常用名: (R)-N-(5-((S)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide
• 英文名: (R)-N-(5-((S)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide
• CAS号: 2409590-08-3
• 分子量: 428.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₂₂F₂N₆O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (R)-N-(5-((S)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide

物理化学性质

• 分子式: C₂₁H₂₂F₂N₆O₂
• 分子量: 428.4
• InChIKey: NYNZQNWKBKUAII-KDOFPFPSSA-N
• SMILES: O=C(Nc1cnn2ccc(N3CCCC3c3cc(F)ccc3F)nc12)N1CCC(O)C1

靶点实验

查看更多实验

实验名称：Inhibition of N-terminal GST-tagged human TRKC (456 to 825 residues) expressed in Sf2... 来源：ChEMBL 靶标：NT-3 growth factor receptor External Id：CHEMBL4840466

实验名称：Inhibition of N-terminal GST-tagged human TRKB (456 to 822 residues) expressed in bac... 来源：ChEMBL 靶标：BDNF/NT-3 growth factors receptor External Id：CHEMBL4840465

实验名称：Selectivity index, ratio of IC50 for inhibition of wildtype TRKA (unknown origin) to ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5053803

实验名称：Selectivity index, ratio of IC50 for inhibition of wildtype TRKA (unknown origin) to ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5053802

实验名称：Selectivity index, ratio of IC50 for inhibition of wildtype TRKA (unknown origin) to ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5053801

实验名称：Inhibition of N-terminal GST-tagged human TRKA (436 to 790 residues) expressed in bac... 来源：ChEMBL 靶标：High affinity nerve growth factor receptor External Id：CHEMBL4840464

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