7-Bromo-4-(2-chloroacetyl)-1-methyl-3H-quinoxalin-2-one

• 常用名: 7-Bromo-4-(2-chloroacetyl)-1-methyl-3H-quinoxalin-2-one
• 英文名: 7-Bromo-4-(2-chloroacetyl)-1-methyl-3H-quinoxalin-2-one
• CAS号: 2411271-44-6
• 分子量: 317.56
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₁H₁₀BrClN₂O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 7-Bromo-4-(2-chloroacetyl)-1-methyl-3H-quinoxalin-2-one

物理化学性质

• 分子式: C₁₁H₁₀BrClN₂O₂
• 分子量: 317.56
• InChIKey: GCGLJIKWBLMOBK-UHFFFAOYSA-N
• SMILES: CN1C(=O)CN(C(=O)CCl)c2ccc(Br)cc21

靶点实验

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实验名称：Induction of GSH depletion in human HepG2 cells at <10 uM measured after 22 hrs by GS... 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL5634431

实验名称：Induction of GSH depletion in human HepG2 cells at >10 uM measured after 22 hrs by GS... 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL5634432

实验名称：Inhibition of recombinant caspase-2 (unknown origin) at 12.5 uM using Z-VDVAD-AFC as ... 来源：ChEMBL 靶标：Caspase-2 External Id：CHEMBL5634421

实验名称：Inhibition of recombinant caspase-2 (unknown origin) at 6.25 uM using Z-VDVAD-AFC as ... 来源：ChEMBL 靶标：Caspase-2 External Id：CHEMBL5634422

实验名称：Inhibition of recombinant caspase-3 (unknown origin) at 125 uM using Z-VDVAD-AFC as s... 来源：ChEMBL 靶标：Caspase-3 External Id：CHEMBL5634423

实验名称：Inhibition of recombinant caspase-3 (unknown origin) at 62.5 uM using Z-VDVAD-AFC as ... 来源：ChEMBL 靶标：Caspase-3 External Id：CHEMBL5634424

实验名称：Inhibition of recombinant caspase-3 (unknown origin) using Z-VDVAD-AFC as substrate m... 来源：ChEMBL 靶标：Caspase-3 External Id：CHEMBL5634426

实验名称：Selectivity ratio of IC50 for recombinant caspase-3 (unknown origin) to recombinant c... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5634427

实验名称：Irreversible inhibition of recombinant caspase-2 (unknown origin) assessed as ratio o... 来源：ChEMBL 靶标：Caspase-2 External Id：CHEMBL5634428

实验名称：Covalent irreversible binding affinity to recombinant caspase-2 (unknown origin) asse... 来源：ChEMBL 靶标：Caspase-2 External Id：CHEMBL5634429

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