2-[(4-Methoxypyridin-2-yl)methyl]-7-[(2-methylimidazol-1-yl)methyl]-5-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]-3,4-dihydroisoquinolin-1-one

• 常用名: 2-[(4-Methoxypyridin-2-yl)methyl]-7-[(2-methylimidazol-1-yl)methyl]-5-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]-3,4-dihydroisoquinolin-1-one
• 英文名: 2-[(4-Methoxypyridin-2-yl)methyl]-7-[(2-methylimidazol-1-yl)methyl]-5-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]-3,4-dihydroisoquinolin-1-one
• CAS号: 2417009-99-3
• 分子量: 510.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₆H₂₅F₃N₆O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-[(4-Methoxypyridin-2-yl)methyl]-7-[(2-methylimidazol-1-yl)methyl]-5-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]-3,4-dihydroisoquinolin-1-one

物理化学性质

• 分子式: C₂₆H₂₅F₃N₆O₂
• 分子量: 510.5
• InChIKey: YGNFBQUKKVHYGI-UHFFFAOYSA-N
• SMILES: COc1ccnc(CN2CCc3c(cc(Cn4ccnc4C)cc3-c3cn(C)nc3C(F)(F)F)C2=O)c1

靶点实验

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实验名称：Anti-proliferative activity against human MV4-11 cells assessed as inhibition of cell... 来源：ChEMBL 靶标：MV4-11 External Id：CHEMBL5165199

实验名称：Metabolic stability of compound in rat liver microsome assessed as intrinsic clearanc... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5165209

实验名称：Anti-proliferative activity against human MOLM-13 cells assessed as inhibition of cel... 来源：ChEMBL 靶标：MOLM-13 External Id：CHEMBL5165208

实验名称：Selectivity ratio of GI50 for human K562 cells to GI50 for human MV4-11 cells 来源：ChEMBL 靶标：N/A External Id：CHEMBL5165210

实验名称：Metabolic stability of compound in rat liver microsome assessed as half life at 1 uM ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5165189

实验名称：Competitive binding affinity to N-terminal 6xHis-SUMO-tagged human WDR5 (22 to 334 re... 来源：ChEMBL 靶标：WD repeat-containing protein 5 External Id：CHEMBL5165207

实验名称：Anti-proliferative activity against human K562 cells assessed as inhibition of cell p... 来源：ChEMBL 靶标：K562 External Id：CHEMBL5165200

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