(R)-12-((S)-(3,4-difluorophenyl)(phenyl)methyl)-7-hydroxy-3,4,12,12a-tetrahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-6,8-dione

• 常用名: (R)-12-((S)-(3,4-difluorophenyl)(phenyl)methyl)-7-hydroxy-3,4,12,12a-tetrahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-6,8-dione
• 英文名: (R)-12-((S)-(3,4-difluorophenyl)(phenyl)methyl)-7-hydroxy-3,4,12,12a-tetrahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-6,8-dione
• CAS号: 2417852-00-5
• 分子量: 439.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₁₉F₂N₃O₄
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (R)-12-((S)-(3,4-difluorophenyl)(phenyl)methyl)-7-hydroxy-3,4,12,12a-tetrahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-6,8-dione

物理化学性质

• 分子式: C₂₃H₁₉F₂N₃O₄
• 分子量: 439.4
• InChIKey: QGJKYYMJOKSGBH-UXHICEINSA-N
• SMILES: C1COC[C@@H]2N1C(=O)C3=C(C(=O)C=CN3N2[C@@H](C4=CC=CC=C4)C5=CC(=C(C=C5)F)F)O

靶点实验

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实验名称：Stability in human liver S9 fraction assessed as parent compound remaining at 1 uM me... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626806

实验名称：Stability in human plasma assessed as parent compound remaining at 1 uM measured afte... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626805

实验名称：Stability in rat liver S9 fraction assessed as parent compound remaining at 1 uM meas... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626808

实验名称：Stability in rat plasma assessed as parent compound remaining at 1 uM measured after ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626807

实验名称：Stability in mouse liver S9 fraction assessed as parent compound remaining at 1 uM me... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626810

实验名称：Stability in mouse plasma assessed as parent compound remaining at 1 uM measured afte... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626809

实验名称：Inhibition of CEN polymerase activity in Influenza A/California/04/2009 (H1N1)pdm09 N... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626574

实验名称：Ratio of AUClast in CD1 mouse lung to plasma at 10 mg/kg, po administered as single d... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626638

实验名称：Inhibition of CEN polymerase activity in Influenza A/California/04/2009 (H1N1)pdm09 N... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626573

实验名称：Ratio of Cmax in CD1 mouse lung to plasma at 10 mg/kg, po administered as single dose... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4626637

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