USP1-IN-1

• 常用名: USP1-IN-1
• 英文名: USP1-IN-1
• CAS号: 2446480-97-1
• 分子量: 534.54
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₇H₂₅F₃N₈O
• 熔点: N/A
• 闪点: N/A

USP1-IN-1用途

USP1-IN-1(式I)是一种USP1和PARP抑制剂(从专利WO2021163530中提取)。

USP1-IN-1名称

• 英文名: USP1-IN-1

USP1-IN-1生物活性

• 描述: USP1-IN-1(式I)是一种USP1和PARP抑制剂(从专利WO2021163530中提取)。
• 相关类别:
  信号通路 >> 表观遗传学 >> PARP
  研究领域 >> 其他
  信号通路 >> 细胞周期/DNA损伤 >> PARP
• 参考文献:

  [1]. WYLIE, et al. THERAPEUTIC COMBINATIONS COMPRISING UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 1 (USP1) INHIBITORS AND POLY (ADP-RIBOSE) POLYMERASE (PARP) INHIBITORS. WO2021163530.

USP1-IN-1物理化学性质

• 分子式: C₂₇H₂₅F₃N₈O
• 分子量: 534.54

USP1-IN-1靶点实验

查看更多实验

实验名称：Thermal stabilization of human USP1 assessed as increase in melting temperature at 50... 来源：ChEMBL 靶标：Ubiquitin carboxyl-terminal hydrolase 1 External Id：CHEMBL5588831

实验名称：Thermal stabilization of full length human USP1 at 50 uM by SYPRO orange dye based th... 来源：ChEMBL 靶标：Ubiquitin carboxyl-terminal hydrolase 1 External Id：CHEMBL5588832

实验名称：Thermal stabilization of human His6 tagged/TEV fused USP1 229 to 408/608 to 737 resid... 来源：ChEMBL 靶标：Ubiquitin carboxyl-terminal hydrolase 1 External Id：CHEMBL5588833

实验名称：Thermal stabilization of human His6-smt3 fused USP7 catalytic domain (208 to 560 resi... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5588834

实验名称：Inhibition of human USP1-mediated catalysis assessed as reduction in reaction between... 来源：ChEMBL 靶标：Ubiquitin carboxyl-terminal hydrolase 1 External Id：CHEMBL5588835

实验名称：Inhibition of human USP1-mediated catalysis assessed as reduction in reaction between... 来源：ChEMBL 靶标：Ubiquitin carboxyl-terminal hydrolase 1 External Id：CHEMBL5588836

实验名称：Binding affinity to human His6 tagged/TEV fused USP1 229 to 408/608 to 737 residues d... 来源：ChEMBL 靶标：Ubiquitin carboxyl-terminal hydrolase 1 External Id：CHEMBL5588837

实验名称：Binding affinity to human His6 tagged/TEV fused USP1 229 to 408/608 to 737 residues d... 来源：ChEMBL 靶标：Ubiquitin carboxyl-terminal hydrolase 1 External Id：CHEMBL5588838

实验名称：Inhibition of human USP12 at 100 uM by ubiquitin-rhodamine assay relative to control 来源：ChEMBL 靶标：Ubiquitin carboxyl-terminal hydrolase 12 External Id：CHEMBL5588841

实验名称：Inhibition of human USP46 at 100 uM by ubiquitin-rhodamine assay relative to control 来源：ChEMBL 靶标：Ubiquitin carboxyl-terminal hydrolase 46 External Id：CHEMBL5588842

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