BuChE-IN-4

• 常用名: BuChE-IN-4
• 英文名: BuChE-IN-4
• CAS号: 2499490-52-5
• 分子量: 510.38
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₂₁BrFN₃O₄S
• 熔点: N/A
• 闪点: N/A

BuChE-IN-4用途

BuChE-IN-4(化合物C6)是一种有效的BuChE抑制剂,IC50为7.7 nM。BuChE-IN-4具有温和的抗氧化能力、无毒性、亲脂性和神经保护活性[1]。

BuChE-IN-4名称

• 英文名: BuChE-IN-4

BuChE-IN-4生物活性

• 描述: BuChE-IN-4(化合物C6)是一种有效的BuChE抑制剂,IC50为7.7 nM。BuChE-IN-4具有温和的抗氧化能力、无毒性、亲脂性和神经保护活性[1]。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Zhang Z, et al. The structure-based optimization of δ-sultone-fused pyrazoles as selective BuChE inhibitors. Eur J Med Chem. 2020 Sep 1;201:112273.

BuChE-IN-4物理化学性质

• 分子式: C₂₁H₂₁BrFN₃O₄S
• 分子量: 510.38

BuChE-IN-4靶点实验

查看更多实验

实验名称：Inhibition of recombinant electric eel AChE using acetylthiocholine iodide as substra... 来源：ChEMBL 靶标：Acetylcholinesterase External Id：CHEMBL4708127

实验名称：Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincu... 来源：ChEMBL 靶标：Cholinesterase External Id：CHEMBL4708126

实验名称：Reversible inhibition of equine serum BChE using butyrylthiolcholine iodide as substr... 来源：ChEMBL 靶标：Cholinesterase External Id：CHEMBL4708129

实验名称：Antioxidant activity assessed as free radical scavenging activity at 100 uM measured ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4708128

实验名称：Octanol/Water partition coefficient, log P of the compound in PBS buffer at pH7.4 mea... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4708131

实验名称：Selectivity for equine serum BuChE over recombinant electric eel AChE 来源：ChEMBL 靶标：N/A External Id：CHEMBL4708140

实验名称：Cytotoxicity against human L02 cells assessed as reduction in cell viability at 50 uM... 来源：ChEMBL 靶标：L02 External Id：CHEMBL4708133

实验名称：Cytotoxicity against human HepG2 cells assessed as reduction in cell viability at 50 ... 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL4708132

实验名称：Neuroprotective activity against H2O2 induced cytotoxicity in human PC12 cells assess... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4708135

实验名称：Neuroprotective activity against H2O2 induced cytotoxicity in human PC12 cells assess... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4708134

共13条，当前第1页，共2页

1

2