7-氯-N-[3-[[(1,1-二甲基乙基)氨基]甲基]-4-氟苯基]-4-喹啉胺

• 常用名: 7-氯-N-[3-[[(1,1-二甲基乙基)氨基]甲基]-4-氟苯基]-4-喹啉胺
• 英文名: 7-Chloro-N-(4-fluoro-3-{[(2-methyl-2-propanyl)amino]methyl}phenyl )-4-quinolinamine
• CAS号: 260540-97-4
• 分子量: 357.85200
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₂₁ClFN₃
• 熔点: N/A
• 闪点: N/A

名称

• 中文名: 7-氯-N-[3-[[(1,1-二甲基乙基)氨基]甲基]-4-氟苯基]-4-喹啉胺
• 英文名: 7-Chloro-N-(4-fluoro-3-{[(2-methyl-2-propanyl)amino]methyl}phenyl )-4-quinolinamine

物理化学性质

• 分子式: C₂₀H₂₁ClFN₃
• 分子量: 357.85200
• 精确质量: 357.14100
• PSA: 36.95000
• LogP: 6.12290
• InChIKey: OKGGBPZMSDNNFA-UHFFFAOYSA-N
• SMILES: CC(C)(C)NCc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1F

靶点实验

查看更多实验

实验名称：Antimalarial activity against chloroquine-sensitive Plasmodium falciparum 3D7 来源：ChEMBL 靶标：Plasmodium falciparum External Id：CHEMBL958383

实验名称：ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania ... 来源：ChEMBL 靶标：Glucose transporter External Id：CHEMBL3436044

实验名称：Antimalarial activity against chloroquine-resistant Plasmodium falciparum TM6 来源：ChEMBL 靶标：Plasmodium falciparum External Id：CHEMBL958384

实验名称：ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania ... 来源：ChEMBL 靶标：Solute carrier family 2, facilitated glucose transporter member 1 External Id：CHEMBL3436042

实验名称：ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania ... 来源：ChEMBL 靶标：Hexose transporter 1 External Id：CHEMBL3436043

实验名称：Vacuolar accumulation ratio in pH 5.2 digestive vacuole 来源：ChEMBL 靶标：N/A External Id：CHEMBL1014531

实验名称：Lipid accumulation ratio in pH 5.2 digestive vacuole 来源：ChEMBL 靶标：N/A External Id：CHEMBL1014532

实验名称：Binding affinity to heme assessed as binding constant for stepwise binding of 2 molec... 来源：ChEMBL 靶标：Heme External Id：CHEMBL1031632

实验名称：Inhibition of beta-hematin formation as molar equivalent relative to hemin causing bl... 来源：ChEMBL 靶标：Histidine-rich protein PFHRP-II External Id：CHEMBL1031633

实验名称：Antimalarial activity as minimal concentration for parasite elimination at day 23 aga... 来源：ChEMBL 靶标：Plasmodium yoelii External Id：CHEMBL1031630

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