MMV688844

• 常用名: MMV688844
• 英文名: MMV688844
• CAS号: 2650213-59-3
• 分子量: 424.929
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₂₅ClN₄O₂
• 熔点: N/A
• 闪点: N/A

MMV688844用途

MMV688844(MMV844)是一种哌啶-4-甲酰胺,对脓肿分枝杆菌具有杀菌作用,靶向分枝杆菌DNA旋转酶。

MMV688844名称

• 英文名: MMV688844

MMV688844生物活性

• 描述: MMV688844(MMV844)是一种哌啶-4-甲酰胺,对脓肿分枝杆菌具有杀菌作用,靶向分枝杆菌DNA旋转酶。
• 参考文献: 1. Jeong J, et al. PLoS One. 2018 Apr 26;13(4):e0195595. 2. Negatu DA, et al. Antimicrob Agents Chemother. 2021 Jul 16;65(8):e0067621. 3. Beuchel A, et al. ACS Med Chem Lett. 2022 Feb 28;13(3):417-427.

MMV688844物理化学性质

• 分子式: C₂₃H₂₅ClN₄O₂
• 分子量: 424.929

MMV688844靶点实验

查看更多实验

实验名称：HepG2 galactose CC50 (uM) Cytotoxicity 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL3832836

实验名称：HepG2 glucose CC50 (uM) Cytotoxicity 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL3832837

实验名称：GSK_TB: Inhibition of the intracellular growth of Mycobacterium tuberculosis (pXC50) 来源：ChEMBL 靶标：Mycobacterium tuberculosis H37Rv External Id：CHEMBL3637833

实验名称：GSK_TB: Effect of compound calculated as % inhibition at single shot or pIC50 ( pIC50... 来源：ChEMBL 靶标：Mycobacterium tuberculosis variant bovis External Id：CHEMBL3637832

实验名称：GSK_TB: Minimum inhibitory concentration against H37Rv stain of Mycobacterium tubercu... 来源：ChEMBL 靶标：Mycobacterium tuberculosis H37Rv External Id：CHEMBL3637831

实验名称：Antibacterial activity against Staphylococcus aureus MRSA ATCC 43300 (CO-ADD:GP_020);... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4296184

实验名称：GSK_TB: Kinetic solubility of the compound in phosphate buffered saline at pH 7.4 aft... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3637838

实验名称：GSK_TB: The cytotoxicity against HepG2 cells expressed as IC50 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL3637837

实验名称：Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); ... 来源：ChEMBL 靶标：Klebsiella pneumoniae External Id：CHEMBL4296186

实验名称：GSK_TB: Growth inhibition of non-replicating Mycobacterium tuberculosis (pXC50) 来源：ChEMBL 靶标：Mycobacterium tuberculosis H37Rv External Id：CHEMBL3637836

共51条，当前第1页，共6页

1

2

3

4

5