p38 MAP激酶抑制剂V

• 常用名: p38 MAP激酶抑制剂V
• 英文名: 4-[3-(4-chlorophenyl)-5-(1-methylpiperidin-4-yl)-1H-pyrazol-4-yl]pyrimidine
• CAS号: 271576-77-3
• 分子量: 353.84900
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₂₀ClN₅
• 熔点: N/A
• 闪点: N/A

p38 MAP激酶抑制剂V名称

• 中文名: p38 MAP激酶抑制剂V
• 英文名: 4-[3-(4-chlorophenyl)-5-(1-methylpiperidin-4-yl)-1H-pyrazol-4-yl]pyrimidine

p38 MAP激酶抑制剂V物理化学性质

• 分子式: C₁₉H₂₀ClN₅
• 分子量: 353.84900
• 精确质量: 353.14100
• PSA: 57.70000
• LogP: 3.93420
• InChIKey: WYWOBCJMDNZHAV-UHFFFAOYSA-N
• SMILES: CN1CCC(c2[nH]nc(-c3ccc(Cl)cc3)c2-c2ccncn2)CC1

p38 MAP激酶抑制剂V靶点实验

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实验名称：Antiarthritic activity against collagen-induced arthritis in DBA/1 mouse chronic CIA ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL1107056

实验名称：Displacement of dofetilide from human ERG at 10 uM 来源：ChEMBL 靶标：Potassium voltage-gated channel subfamily H member 2 External Id：CHEMBL1107054

实验名称：Half life in human liver microsomes 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL1107053

实验名称：Intrinsic clearance in human liver microsomes 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL1107052

实验名称：Antiinflammatory activity against LPS-induced TNFalpha production in human whole bloo... 来源：ChEMBL 靶标：Blood External Id：CHEMBL1107051

实验名称：Antiinflammatory activity in Lewis rat assessed as reduction in LPS-stimulated TNFalp... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1107050

实验名称：Antiinflammatory activity in Lewis rat plasma assessed as reduction in LPS-stimulated... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1107048

实验名称：Inhibition of p38beta assessed as gamma-[33P]ATP incorporation by scintillation count... 来源：ChEMBL 靶标：Mitogen-activated protein kinase 11 External Id：CHEMBL1107047

实验名称：Inhibition of p38alpha assessed as gamma-[33P]ATP incorporation by scintillation coun... 来源：ChEMBL 靶标：Mitogen-activated protein kinase 14 External Id：CHEMBL1107046

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p38 MAP激酶抑制剂V英文别名

• 5-(N-METHYL-4-PIPERIDYL)-4-(4-PYRIMIDYL)-3-(4-CHLOROPHENYL)PYRAZOLE
• p38 MAP Kinase Inhibitor V