US11345681, Example 13

• 常用名: US11345681, Example 13
• 英文名: US11345681, Example 13
• CAS号: 2750709-24-9
• 分子量: 487.6
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₆H₂₉N₇O₃
• 熔点: N/A
• 闪点: N/A

US11345681, Example 13名称

• 英文名: US11345681, Example 13

US11345681, Example 13物理化学性质

• 分子式: C₂₆H₂₉N₇O₃
• 分子量: 487.6
• InChIKey: CJVVXRNKGDZSSX-RBUKOAKNSA-N
• SMILES: CNC1=C(C(=NN1[C@H]2C[C@@H](N(C2)C(=O)C=C)COC)C#CC3=CC4=C(C=C3)N(C=N4)C5CC5)C(=O)N

US11345681, Example 13靶点实验

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实验名称：Inhibition of FGFR3 V555M mutant (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 pepti... 来源：ChEMBL 靶标：Fibroblast growth factor receptor 3 External Id：CHEMBL5541342

实验名称：Inhibition of FGFR3 K650M mutant (unknown origin) using 5-FAM-KKKKEEIYFFF-CONH2 pepti... 来源：ChEMBL 靶标：Fibroblast growth factor receptor 3 External Id：CHEMBL5541343

实验名称：Half life in Sprague-Dawley rat at 5 mg/kg,iv administrated at 0.25 to 24 hrs by LC-M... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5541357

实验名称：Total clearance in Sprague-Dawley rat at 5 mg/kg,iv administrated at 0.25 to 24 hrs b... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5541358

实验名称：AUC (0 to 24 hrs) in Sprague-Dawley rat at 15 mg/kg,po administrated at 0.25 to 24 hr... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5541360

实验名称：Oral bioavailability in Sprague-Dawley rat at 15 mg/kg administrated at 0.25 to 24 hr... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5541361

实验名称：Half life in Beagle dog at 5 mg/kg,iv administrated at 0.25 to 24 hrs by LC-MS/MS ana... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5541362

实验名称：Total clearance in Beagle dog at 5 mg/kg,iv administrated at 0.25 to 24 hrs by LC-MS/... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5541363

实验名称：FGFR2 Kinase Assay from US Patent US11345681: "Inhibitors of fibroblast growth factor... 来源：BindingDB 靶标：N/A External Id：BindingDB_10634_1

实验名称：Cmax in Beagle dog at 10 mg/kg,po administrated at 0.25 to 24 hrs by LC-MS/MS analysi... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5541367

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