(2E,4E)-5-(4-Hydroxy-3-methoxyphenyl)-2-phenyl-1-(4-(pyrimidin-2-yl)piperazin-1-yl)penta-2,4-dien-1-one

• 常用名: (2E,4E)-5-(4-Hydroxy-3-methoxyphenyl)-2-phenyl-1-(4-(pyrimidin-2-yl)piperazin-1-yl)penta-2,4-dien-1-one
• 英文名: (2E,4E)-5-(4-Hydroxy-3-methoxyphenyl)-2-phenyl-1-(4-(pyrimidin-2-yl)piperazin-1-yl)penta-2,4-dien-1-one
• CAS号: 2761706-47-0
• 分子量: 442.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₆H₂₆N₄O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (2E,4E)-5-(4-Hydroxy-3-methoxyphenyl)-2-phenyl-1-(4-(pyrimidin-2-yl)piperazin-1-yl)penta-2,4-dien-1-one

物理化学性质

• 分子式: C₂₆H₂₆N₄O₃
• 分子量: 442.5
• InChIKey: WGVSYKBTUWJQKN-YZLBAONLSA-N
• SMILES: COc1cc(C=CC=C(C(=O)N2CCN(c3ncccn3)CC2)c2ccccc2)ccc1O

靶点实验

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实验名称：Metal chelating activity assessed as compound-Fe3+ complex formation at 50 uM by UV-V... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5158557

实验名称：Metal chelating activity assessed as compound-Fe2+ complex formation at 50 uM by UV-V... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5158556

实验名称：Upregulation of RSL-3 induced GPX4 mRNA expression in human HT-22 cells at 1.25 to 5 ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5158559

实验名称：Effect on intracellular GSH level in human HT-22 cells assessed as increase in GSH le... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5158558

实验名称：Protection against STS-induced apoptosis in human HT-22 cells at 5 uM measured after ... 来源：ChEMBL 靶标：HT-22 External Id：CHEMBL5158553

实验名称：Inhibition of RSL-3 induced Ptgs2 mRNA expression in human HT-22 cells measured after... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5158552

实验名称：Antioxidant activity assessed as free radical scavenging activity incubated for 30 mi... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5158555

实验名称：Protection against H2O2-induced necrosis in human HT-22 cells at 5 uM measured after ... 来源：ChEMBL 靶标：HT-22 External Id：CHEMBL5158554

实验名称：Reduction in ROS accumulation in RSL-3 treated human HT-22 cells assessed as reductio... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5158548

实验名称：Reduction in cytosolic ROS accumulation in RSL-3 treated human HT-22 cells incubated ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5158551

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