Parp-1-IN-1

• 常用名: Parp-1-IN-1
• 英文名: Parp-1-IN-1
• CAS号: 2763840-83-9
• 分子量: 392.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₂₅FN₄O
• 熔点: N/A
• 闪点: N/A

Parp-1-IN-1名称

• 英文名: Parp-1-IN-1

Parp-1-IN-1物理化学性质

• 分子式: C₂₃H₂₅FN₄O
• 分子量: 392.5
• InChIKey: FNXYFOFBZPBUFN-UHFFFAOYSA-N
• SMILES: NC1CCN(Cc2cccc(-c3[nH]c4cc(F)cc5c4c3CCNC5=O)c2)CC1

Parp-1-IN-1靶点实验

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实验名称：Induction of apoptosis in human A549 cells assessed as reduction in PAR level measure... 来源：ChEMBL 靶标：A549 External Id：CHEMBL5132152

实验名称：Antitumor activity against human BRCA1 mutant MDA-MB-436 cells xenografted athymic BA... 来源：ChEMBL 靶标：MDA-MB-436 External Id：CHEMBL5132153

实验名称：Toxicity athymic BALB/c mouse xenografted with human BRCA1 mutant MDA-MB-436 cells as... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5132154

实验名称：In vivo inhibition of PARP1 in athymic BALB/c mouse xenografted with human BRCA1 muta... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5132155

实验名称：Selectivity index, ratio of IC50 for human PARP2 to IC50 for human PARP1 来源：ChEMBL 靶标：N/A External Id：CHEMBL5132148

实验名称：Inhibition of human PARP1 using NAD+ as substrate at 5 nM incubated for 1 hr by ELISA... 来源：ChEMBL 靶标：Poly [ADP-ribose] polymerase 1 External Id：CHEMBL5132144

实验名称：Inhibition of human PARP2 using NAD+ as substrate at 5 nM incubated for 1 hr by ELISA... 来源：ChEMBL 靶标：Poly [ADP-ribose] polymerase 2 External Id：CHEMBL5132145

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