N-[3-[4-amino-5-[1-[2-[3-(trifluoromethoxy)phenyl]acetyl]-2,3-dihydroindol-5-yl]pyrrolo[2,3-d]pyrimidin-7-yl]propyl]-N'-[(2S)-1-[(2S,4R)-4-hydroxy-2-[[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]carbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]dodecanediamide

• 常用名: N-[3-[4-amino-5-[1-[2-[3-(trifluoromethoxy)phenyl]acetyl]-2,3-dihydroindol-5-yl]pyrrolo[2,3-d]pyrimidin-7-yl]propyl]-N'-[(2S)-1-[(2S,4R)-4-hydroxy-2-[[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]carbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]dodecanediamide
• 英文名: N-[3-[4-amino-5-[1-[2-[3-(trifluoromethoxy)phenyl]acetyl]-2,3-dihydroindol-5-yl]pyrrolo[2,3-d]pyrimidin-7-yl]propyl]-N'-[(2S)-1-[(2S,4R)-4-hydroxy-2-[[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]carbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]dodecanediamide
• CAS号: 2782022-40-4
• 分子量: 1149.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₆₁H₇₅F₃N₁₀O₇S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-[3-[4-amino-5-[1-[2-[3-(trifluoromethoxy)phenyl]acetyl]-2,3-dihydroindol-5-yl]pyrrolo[2,3-d]pyrimidin-7-yl]propyl]-N'-[(2S)-1-[(2S,4R)-4-hydroxy-2-[[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]carbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]dodecanediamide

物理化学性质

• 分子式: C₆₁H₇₅F₃N₁₀O₇S
• 分子量: 1149.4
• InChIKey: RMSGROMYBXPAFX-XVYCCKKLSA-N
• SMILES: CC1=C(SC=N1)C2=CC=C(C=C2)[C@H](C)NC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)C)NC(=O)CCCCCCCCCCC(=O)NCCCN4C=C(C5=C(N=CN=C54)N)C6=CC7=C(C=C6)N(CC7)C(=O)CC8=CC(=CC=C8)OC(F)(F)F)O

靶点实验

查看更多实验

实验名称：PROTAC activity at VHL/wild type nLuc-fused N-terminal RIPK1 kinase domain (unknown o... 来源：ChEMBL 靶标：Receptor-interacting serine/threonine-protein kinase 1 External Id：CHEMBL5610775

实验名称：PROTAC activity at VHL/nLucK0-fused N-terminal RIPK1 kinase domain (unknown origin) e... 来源：ChEMBL 靶标：Receptor-interacting serine/threonine-protein kinase 1 External Id：CHEMBL5610777

实验名称：PROTAC activity at VHL/wild type nLuc-fused N-terminal RIPK1 kinase domain (unknown o... 来源：ChEMBL 靶标：Receptor-interacting serine/threonine-protein kinase 1 External Id：CHEMBL5610778

实验名称：PROTAC activity at VHL/nLucK0-fused N-terminal RIPK1 kinase domain (unknown origin) e... 来源：ChEMBL 靶标：Receptor-interacting serine/threonine-protein kinase 1 External Id：CHEMBL5610779

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