6-chloro-3-(1-methyl-1-phenylethyl)amino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide

• 常用名: 6-chloro-3-(1-methyl-1-phenylethyl)amino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide
• 英文名: 6-chloro-3-(1-methyl-1-phenylethyl)amino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide
• CAS号: 279215-50-8
• 分子量: 355.9
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₄H₁₄ClN₃O₂S₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 6-chloro-3-(1-methyl-1-phenylethyl)amino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide

物理化学性质

• 分子式: C₁₄H₁₄ClN₃O₂S₂
• 分子量: 355.9
• InChIKey: XUSQKHZVTSWKMN-UHFFFAOYSA-N
• SMILES: CC(C)(N=C1Nc2cc(Cl)sc2S(=O)(=O)N1)c1ccccc1

靶点实验

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实验名称：Repolarization of HEK293 cells expressing Kir6.2/SUR1 KATP channels 来源：ChEMBL 靶标：ATP-sensitive inward rectifier potassium channel 11 External Id：CHEMBL866794

实验名称：Half life in Sprague-Dawley rat at 2.3 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL869730

实验名称：Inhibition of glucose-stimulated insulin release in Wistar rat islets 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL866792

实验名称：Reduction in plasma insulin level in anaesthetized Sprague-Dawley rat at 3 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL864946

实验名称：Reduction in plasma insulin level in po dosed Zucker obese rat after 2 hrs 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL864947

实验名称：Repolarization of beta-TC3 cells 来源：ChEMBL 靶标：Beta-TC3 External Id：CHEMBL866639

实验名称：Tmax in Sprague-Dawley rat at 2.3 mg/kg, po or 1.24 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL869727

实验名称：Inhibition of glucose-stimulated insulin release in betaTC6 cells 来源：ChEMBL 靶标：Beta-TC6 External Id：CHEMBL866796

实验名称：Oral bioavailability in Sprague-Dawley rat at 2.3 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL869728

实验名称：Inhibition of glucose-stimulated insulin release in beta-TC6 cells at 10 uM 来源：ChEMBL 靶标：Beta-TC6 External Id：CHEMBL866797

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